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                <title xml:lang="pt">LEISHMANIOSE VISCERAL EM PACIENTE PORTADORA DE HEMOGLOBINOPATIA COM COMPLICAÇÃO POR USO DE GLUCANTIME®: DESAFIO DIAGNÓSTICO E TERAPÊUTICO</title>
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                    <forename type="first">Johnatan</forename>
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                    <forename type="first">Mariana</forename>
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                <term xml:lang="en">Glucantime®</term>
                <term xml:lang="en">Hemoglobinopathy SC</term>
                <term xml:lang="en">Visceral Leishmaniasis</term>
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              <p>Visceral Leishmaniasis (VL) is a chronic, severe and systemic protozoonosis caused by different species of the genus Leishmania sp., which results in death in 90% of cases if not treated. Clinical suspicion should be raised when the patient has fever and splenomegaly, associated or not with hepatomegaly. This paper presents the case report of a patient admitted to Dona Regina Siqueira Campos Maternity Hospital, in Palmas, Tocantins, Brazil, with a clinical history of thrombocytopenia and splenomegaly, initially diagnosed and treated as a VL, but later diagnosed with SC Hemoglobinopathy. During pregnancy, women with HbSC genotype may develop complications as severe as those presented by women with HbSS genotype. However, the symptoms presented by this patient at the end of gestation may also be confused with the VL condition, a diagnosis for which she presented two positive laboratory tests.</p>
            </abstract>
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              <p>A leishmaniose visceral (LV) é uma protozoonose de evolução crônica, grave e sistêmica, causada por diferentes espécies do gênero Leishmania sp., que resulta em morte em 90% dos casos se não tratada. A suspeita clínica deve ser levantada quando o paciente apresentar febre e esplenomegalia associada ou não à hepatomegalia. Apresentamos, neste trabalho, o relato de caso de uma paciente que deu entrada no Hospital e Maternidade Dona Regina Siqueira Campos (HMDR), em Palmas, Tocantins (TO), com quadro de plaquetopenia e esplenomegalia e inicialmente diagnosticada e tratada como um quadro de LV e posteriormente diagnosticada com Hemoglobinopatia SC. Durante a gestação, mulheres portadoras do genótipo HbSC podem desenvolver complicações tão graves quanto as apresentadas por mulheres portadoras do genótipo Hb SS. No entanto, os sintomas apresentados pela paciente ao final da gestação podem ser confundidos também com o quadro de LV, diagnóstico para o qual apresentou dois exames laboratoriais positivos.</p>
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