For the 2021 IEEE VR 3DUI contest, the topic of the year is “Challenging Pandemics” with a direct or indirect link to COVID-19. We present Rebirth-20, an immersive application focusing on two axes: breathing and prevention against the spread of the virus. Using an Oculus Quest 2, we have developed a virtual world, enriched with different exercises. A prevention part allows the user to get familiar with gestures for stopping virus spread, such as washing hands and put on a mask. The purpose of the exercises is to help people affected by COVID-19 and having breathing difficulties.