Adhesion as a trigger of droplet polarization in flowing emulsions † - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Soft Matter Année : 2021

Adhesion as a trigger of droplet polarization in flowing emulsions †

Résumé

Tissues are subjected to large external forces and undergo global deformations during morphogenesis. We use synthetic analogues of tissues to study the impact of cell-cell adhesion on the response of cohesive cellular assemblies under such stresses. In particular, we use biomimetic emulsions in which the droplets are functionalized in order to exhibit specific droplet-droplet adhesion. We flow these emulsions in microfluidic constrictions and study their response to this forced deformation via confocal microscopy. We find that the distributions of avalanche sizes are conserved between repulsive and adhesive droplets. However, adhesion locally impairs the rupture of droplet-droplet contacts, which in turn pulls on the rearranging droplets. As a result, adhesive droplets are a lot more deformed along the axis of elongation in the constriction. This finding could shed light on the origin of polarization processes during morphogenesis.
Fichier principal
Vignette du fichier
Golovkova et al. - 2021 - Adhesion as a trigger of droplet polarization in f.pdf (1.07 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03172065 , version 1 (17-03-2021)

Identifiants

Citer

Iaroslava Golovkova, Lorraine Montel, Franck Pan, Elie Wandersman, Alexis Michel Prevost, et al.. Adhesion as a trigger of droplet polarization in flowing emulsions †. Soft Matter, 2021, ⟨10.1039/D1SM00097G⟩. ⟨hal-03172065⟩
70 Consultations
51 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More