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            <title xml:lang="en">Effectiveness of prostaglandin F2a in the initial treatment of bovine ovarian cysts.</title>
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            <idno type="halRefHtml">&lt;i&gt;Theriogenology&lt;/i&gt;, 1993, 40, pp.745-755</idno>
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              <p>This study was conducted to evaluate the use of prostaglandin F2a (PGF2a)in the initial treatment of ovarian cysts in dairy cattle. Two hundred and sixty three cows diagnosed cystic on palpation per rectum were randomly assigned to one of three treatment groups (A, B or C). Cows in Groups A and B were treated with 25 mg i.m.of PGF2a at the time of diagnosis (Day 0). while cows in Group C received 100 pg of GnRH. Seven days following initial treatment (Day 7). cows from Group A that were not observed in estrus were treated with GnRH. Cows from Groups B and C were not treated. On Day 14. all cows that had not been inseminated received PGF2a. A blood sample was obtained from all cows on Days 0, 7 and 14 and was analyzed for progesterone (P4) using radioimmunoassay. Incidences of estrus were recorded and cows that were more than 60 d in milk at the time of diagnosis were bred when observed in estrus.The incidence of follicular cysts on Day 0 (as defined as P4 &lt;0.5 ngjml) was similar between groups and constituted about 40% of all cysts. There were significantly more cows pregnant to insemination within 7 d of initial treatment in Group B than in Groups A and C (PcO.05). After Day 14. the pregnancy rate was not statistically different between Group B and C, but Groups B and C had a statistically higher pregnancy rate than Group A from Day 21 to Day 35. At the end of the study, there was no statistical difference for the pregnancy rate between groups.We concluded that treatment of ovarian cysts diagnosed by per rectum examination with prostaglandin (at time of diagnosis and 14 d later for cows that were not inseminated) was as effective as initial treatment with GnRH followed by prostaglandins 14 d later for cows that were not inseminated previously. Cows that were initially treated with prostaglandins also tended to become pregnant sooner.</p>
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