The CC‐NB‐LRR OsRLR1 mediates rice disease resistance through interaction with OsWRKY19
Résumé
Nucleotide-binding site–leucine-rich repeat (NB-LRR) resistance proteins are critical for plantresistance to pathogens; however, their mechanism of activation and signal transduction is stillnot well understood. We identified a mutation in an as yet uncharacterized rice coiled-coil (CC)-NB-LRR, Oryza sativa RPM1-like resistance gene 1 (OsRLR1), which leads to hypersensitiveresponse (HR)-like lesions on the leaf blade and broad-range resistance to the fungal pathogenPyricularia oryzae (syn. Magnaporthe oryzae) and the bacterial pathogen Xanthomonas oryzaepv. oryzae, together with strong growth reduction. Consistently, OsRLR1-overexpression linesshowed enhanced resistance to both pathogens. Moreover, we found that OsRLR1 mediates thedefence response through direct interaction in the nucleus with the transcription factorOsWRKY19. Down-regulation of OsWRKY19 in the rlr1 mutant compromised the HR-likephenotype and resistance response, and largely restored plant growth. OsWRKY19 binds to thepromoter of OsPR10 to activate the defence response. Taken together, our data highlight therole of a new residue involved in the NB-LRR activation mechanism, allowing identification of anew NB-LRR downstream signalling pathway.
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Plant Biotechnology Journal - 2020 - Du - The CC‐NB‐LRR OsRLR1 mediates rice disease resistance through interaction with.pdf (7.63 Mo)
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