Solvent-free synthesis of unsaturated amino esters in a ball-mill - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Tetrahedron Letters Année : 2010

Solvent-free synthesis of unsaturated amino esters in a ball-mill

Résumé

The ball-milling technique was used solvent-free conditions to perform a Horner-Wadsworth-Emmons reaction in the presence of a mild carbonate base. Starting from a phosphonate-substituted glycine, this method gave access to Boc-protected unsatured amino esters in excellent yield and selectivity in many cases. The scope of the reaction was delineated.
Fichier principal
Vignette du fichier
Hal-64-2010TLBM.pdf (773.09 Ko) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03118824 , version 1 (22-01-2021)

Identifiants

Citer

Alice Baron, Jean Martinez, Frederic Lamaty. Solvent-free synthesis of unsaturated amino esters in a ball-mill. Tetrahedron Letters, 2010, 51, pp.6246-6249. ⟨10.1016/j.tetlet.2010.09.069⟩. ⟨hal-03118824⟩
101 Consultations
115 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More