Ruthenium(II) Complex-Photosensitized Multifunctionalized Porous Silicon Nanoparticles for Two-Photon Near-Infrared Light Responsive Imaging and Photodynamic Cancer Therapy - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Journal of materials chemistry‎ B Année : 2016

Ruthenium(II) Complex-Photosensitized Multifunctionalized Porous Silicon Nanoparticles for Two-Photon Near-Infrared Light Responsive Imaging and Photodynamic Cancer Therapy

Marie Maynadier
  • Fonction : Auteur

Résumé

Multifunctionalized porous silicon nanoparticles (pSiNP) containing novel Ru(II) complex-photosensitizer, polyethylene glycol moiety, and mannose molecules as cancer targeting ligands, are constructed and showcased for application in near infrared (NIR) light-responsive photodynamic therapy (PDT) and imaging of cancer. Exposure to NIR light leads to twophoton excitation of the Ru(II)-complex which allows efficient simultaneous cancer-imaging and targeted PDT therapy with the functionalized biodegradable pSiNP nanocarriers.
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Dates et versions

hal-03116632 , version 1 (20-01-2021)

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Nikola Ž. Knežević, Vanja Stojanovic, Arnaud Chaix, Elise Bouffard, Khaled El Cheikh, et al.. Ruthenium(II) Complex-Photosensitized Multifunctionalized Porous Silicon Nanoparticles for Two-Photon Near-Infrared Light Responsive Imaging and Photodynamic Cancer Therapy. Journal of materials chemistry‎ B, 2016, 4 (7), pp.1337-1342. ⟨10.1039/C5TB02726H⟩. ⟨hal-03116632⟩
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