When individuals are exposed to their own image in a mirror, known to increase self-awareness, they may show increased accessibility of suicide-related words (a phenomenon labeled “the mirror effect”; Selimbegović & Chatard, 2013). We attempted to replicate this effect in a pre-registered study (N = 150). As in the original study, self-awareness was manipulated using a mirror and recognition latencies for accurately detecting suicide-related words, negative words, and neutral words in a lexical decision task were assessed. We found no evidence of the mirror effect in pre-registered analyses. A multiverse analysis revealed a significant mirror effect only when excluding extreme observations. An equivalence TOST test did not yield evidence for or against the mirror effect. Overall, the results suggest that the original effect was a false positive or that the conditions for obtaining it (in terms of statistical power and/or outlier detection method) are not yet fully understood. Implications for the mirror effect and recommendations for pre-registered replications are discussed.