Article Dans Une Revue Equine Veterinary Journal Année : 2020

Determination of the pharmacokinetic‐pharmacodynamic cut‐off values of marbofloxacin in horses to support the establishment of a clinical breakpoint for antimicrobial susceptibility testing

Résumé

Marbofloxacin (MBX), a fluoroquinolone (FQ), is considered as a critical antibiotic requiring antimicrobial susceptibility testing (AST) for prudent use. No clinical breakpoint (CBP) currently exists to interpret the results of such tests in horses.

No clinical data are taken into account in the determination of a PK/PDco .

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Dates et versions

hal-03113834 , version 1 (18-01-2021)

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Alain Bousquet‐mélou, Marc Schneider, Farid El Garch, Diane Broussou, Aude Ferran, et al.. Determination of the pharmacokinetic‐pharmacodynamic cut‐off values of marbofloxacin in horses to support the establishment of a clinical breakpoint for antimicrobial susceptibility testing. Equine Veterinary Journal, 2020, ⟨10.1111/evj.13385⟩. ⟨hal-03113834⟩
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