Salt exploitation from the mineral spring of Halabutoaia-Tolici (Neamt, Romania) is one of the earliest in Europe. Salt production is documented from the Early Neolithic to the end of Chalcolithic period (6000-3500 BC) with an important stratigraphy of 8 m high. In 2008, a core drilling was performed in the salty swamp of the spring closed to archaeological site. Pollen analysis and the study of non-pollen palynomorphs suggest a very anthropic environment since the Early Neolithic. Salt exploitation, agriculture and pastoralism (presence of spores of coprophilous fungi) are directly in connection with these variations. After this intense exploitation, human impact is always perceptible in spite of reforestation.