In this study, a multi-technique approach was developed to characterize the different components within gilt leather. A series of 40 gilt-leather hangings from different countries made between the 16th and 18th centuries were selected for analysis to learn about the manufacturing techniques and to better understand their degradation process. The analytical methodology had to take into account the complexity of the material with the presence of thin multilayers made of organic and inorganic compounds. Techniques that could provide non-or micro-destructive identification, high-sensitivity, and high spatial resolution were employed, that is: ion beam analysis, synchrotron infrared spectroscopy, scanning electron micros-Multi-technique analysis of gilt-leather wall coverings (16th-18th centuries)