Translation of Simultaneous Vessel Wall Motion and Vectorial Blood Flow Imaging in Healthy and Diseased Carotids to the Clinic: a Pilot Study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control Année : 2020

Translation of Simultaneous Vessel Wall Motion and Vectorial Blood Flow Imaging in Healthy and Diseased Carotids to the Clinic: a Pilot Study

Vincent Perrot
Ingvild Kinn Ekroll
  • Fonction : Auteur
Jørgen Avdal
  • Fonction : Auteur
Lars Mølgaard Saxhaug
  • Fonction : Auteur
Håvard Dalen
  • Fonction : Auteur
Didier Vray
Lasse Løvstakken
  • Fonction : Auteur
Herve Liebgott

Résumé

This study aims to investigate the clinical feasibility of simultaneous extraction of vessel wall motion and vectorial blood flow at high frame rates for extraction of clinical markers. If available in the clinic, such a technique would allow better estimation of plaque vulnerability and evaluation of overall arterial health of patients. In this study, both healthy and patient volunteers were recruited and scanned using a plane-wave acquisition scheme that provided a dataset of 43 carotid recordings in total. The vessel wall motion is extracted based on the complex autocorrelation of the signals received, while the vector flow is extracted using the transverse oscillation technique. Wall motion and vector flow are extracted at high frame rates, which allows visual appreciation of tissue movement and blood flow simultaneously and with fine temporal resolution. Several clinical markers are extracted, along with p-values. From all of the potential markers, young healthy volunteers have smaller artery diameter (7.32 mm) compared to diseased patients (9.56 mm), 66 % of diseased patients have backflow, a carotid with a pulse wave velocity extracted from the wall velocity that is greater than 7 m/s is always a diseased vessel, and the peak wall shear rate decreases as the risk increases. Based on both the pathological markers and the visual inspection of tissue motion and vector flow, we conclude that the clinical feasibility of this approach is demonstrated. Larger and more disease-specific studies using such an approach will lead to better understanding and evaluation of vessels, which can translate to future use in the clinic.
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Dates et versions

hal-03024611 , version 1 (25-11-2020)

Identifiants

  • HAL Id : hal-03024611 , version 1

Citer

Vincent Perrot, Ingvild Kinn Ekroll, Jørgen Avdal, Lars Mølgaard Saxhaug, Håvard Dalen, et al.. Translation of Simultaneous Vessel Wall Motion and Vectorial Blood Flow Imaging in Healthy and Diseased Carotids to the Clinic: a Pilot Study. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2020. ⟨hal-03024611⟩
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