Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
Résumé
Highlights d Pro-apoptotic BH3-only proteins and chemotherapy can trigger failed apoptosis d Melanoma cells undergoing failed apoptosis are more invasive in vitro and in vivo d This pro-invasion program is regulated by JNK-AP1 d The failed apoptosis gene signature can discriminate metastatic melanoma
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