<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-02997802</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-04-27T14:36:09+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Machine Learning to Improve the Sensing of Biomolecules by Conical Track-Etched Nanopore</title>
            <author role="aut">
              <persName>
                <forename type="first">Nathan</forename>
                <surname>Meyer</surname>
              </persName>
              <email type="md5">e0858f9c9335a7eee659ca976ed5a18f</email>
              <email type="domain">umontpellier.fr</email>
              <idno type="idhal" notation="numeric">1547054</idno>
              <idno type="halauthorid" notation="string">2064902-1547054</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=ch9dtl4AAAAJ</idno>
              <affiliation ref="#struct-1087310"/>
              <affiliation ref="#struct-1087121"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Marc</forename>
                <surname>Janot</surname>
              </persName>
              <email type="md5">b8afe5e9acb70769d12b9193d3580df7</email>
              <email type="domain">umontpellier.fr</email>
              <idno type="idhal" notation="string">jean-marc-janot</idno>
              <idno type="idhal" notation="numeric">16744</idno>
              <idno type="halauthorid" notation="string">42965-16744</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/G-3217-2012</idno>
              <idno type="IDREF">https://www.idref.fr/031208835</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0663-2995</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/G-3217-2012</idno>
              <affiliation ref="#struct-1087310"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mathilde</forename>
                <surname>Lepoitevin</surname>
              </persName>
              <email type="md5">078251d1f6b4d28067afef8b053965b0</email>
              <email type="domain">brown.edu</email>
              <idno type="idhal" notation="string">mathilde-lepoitevin</idno>
              <idno type="idhal" notation="numeric">17221</idno>
              <idno type="halauthorid" notation="string">17036-17221</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-0244-9939</idno>
              <idno type="IDREF">https://www.idref.fr/225779811</idno>
              <idno type="VIAF">https://viaf.org/viaf/457152636139220050455</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/D-1489-2016</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/D-1489-2016</idno>
              <affiliation ref="#struct-522138"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Michael</forename>
                <surname>Smietana</surname>
              </persName>
              <email type="md5">81ab955a8af90516401d7f8adf758f4a</email>
              <email type="domain">umontpellier.fr</email>
              <idno type="idhal" notation="string">michael-smietana</idno>
              <idno type="idhal" notation="numeric">756205</idno>
              <idno type="halauthorid" notation="string">132468-756205</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8132-7221</idno>
              <idno type="IDREF">https://www.idref.fr/059806591</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/F-7828-2016</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=9yofNMEAAAAJ</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/F-7828-2016</idno>
              <affiliation ref="#struct-24488"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Jacques</forename>
                <surname>Vasseur</surname>
              </persName>
              <email type="md5">a09fe1c7c0bc71361d6718947b1ccb17</email>
              <email type="domain">umontpellier.fr</email>
              <idno type="idhal" notation="string">jean-jacques-vasseur</idno>
              <idno type="idhal" notation="numeric">176784</idno>
              <idno type="halauthorid" notation="string">125487-176784</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-4379-6139</idno>
              <idno type="IDREF">https://www.idref.fr/068903847</idno>
              <affiliation ref="#struct-24488"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Joan</forename>
                <surname>Torrent</surname>
              </persName>
              <email type="md5">63d21716f01397cafc7ae35eeac628dd</email>
              <email type="domain">univ-montp2.fr</email>
              <idno type="idhal" notation="numeric">871775</idno>
              <idno type="halauthorid" notation="string">468659-871775</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-6908-4084</idno>
              <idno type="IDREF">https://www.idref.fr/24059391X</idno>
              <idno type="VIAF">https://viaf.org/viaf/3593157583857133970007</idno>
              <affiliation ref="#struct-1087121"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sebastien</forename>
                <surname>Balme</surname>
              </persName>
              <email type="md5">aadc014d38c6e9587dcfb5f4d730a532</email>
              <email type="domain">umontpellier.fr</email>
              <idno type="idhal" notation="string">sbalme</idno>
              <idno type="idhal" notation="numeric">16743</idno>
              <idno type="halauthorid" notation="string">35976-16743</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-0779-3384</idno>
              <idno type="IDREF">https://www.idref.fr/074013122</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8631-5334</idno>
              <affiliation ref="#struct-1087310"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Jean-Jacques</forename>
                <surname>Vasseur</surname>
              </persName>
              <email type="md5">a09fe1c7c0bc71361d6718947b1ccb17</email>
              <email type="domain">umontpellier.fr</email>
            </editor>
            <funder ref="#projanr-53360"/>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2020-11-10 11:32:00</date>
              <date type="whenModified">2025-08-28 03:15:25</date>
              <date type="whenReleased">2020-11-20 09:55:42</date>
              <date type="whenProduced">2020-10-05</date>
              <date type="whenEndEmbargoed">2020-11-10</date>
              <ref type="file" target="https://hal.science/hal-02997802v1/document">
                <date notBefore="2020-11-10"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://hal.science/hal-02997802v1/file/biosensors-10-00140-v2-1.pdf" id="file-2997802-2655483">
                <date notBefore="2020-11-10"/>
              </ref>
              <ref type="externalLink" target="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601669"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="766366">
                <persName>
                  <forename>Jean-Jacques</forename>
                  <surname>Vasseur</surname>
                </persName>
                <email type="md5">a09fe1c7c0bc71361d6718947b1ccb17</email>
                <email type="domain">umontpellier.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-02997802</idno>
            <idno type="halUri">https://hal.science/hal-02997802</idno>
            <idno type="halBibtex">meyer:hal-02997802</idno>
            <idno type="halRefHtml">&lt;i&gt;Biosensors&lt;/i&gt;, 2020, 10 (10), pp.140. &lt;a target="_blank" href="https://dx.doi.org/10.3390/bios10100140"&gt;&amp;#x27E8;10.3390/bios10100140&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Biosensors, 2020, 10 (10), pp.140. &amp;#x27E8;10.3390/bios10100140&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by/4.0/">CC BY 4.0 - Attribution<ref corresp="#file-2997802-2655483"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="ENS-PARIS">Ecole Normale Supérieure de Paris</idno>
            <idno type="stamp" n="ESPCI">ESPCI Paris-PSL</idno>
            <idno type="stamp" n="EPHE">École Pratique des Hautes Études</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="ENSC-MONTPELLIER">Ecole Nationale Supérieure de Chimie de Montpellier</idno>
            <idno type="stamp" n="IBMM">Institut des Biomolécules Max Mousseron</idno>
            <idno type="stamp" n="MMDN">Mécanismes moléculaires dans les démences neurodégénératives</idno>
            <idno type="stamp" n="IEM">Institut Européen des membranes</idno>
            <idno type="stamp" n="PARISTECH">ParisTech</idno>
            <idno type="stamp" n="INC-CNRS">Institut de Chimie du CNRS</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="BS">Biologie-Santé</idno>
            <idno type="stamp" n="CHIMIE">Chimie</idno>
            <idno type="stamp" n="UNIV-MONTPELLIER">Université de Montpellier</idno>
            <idno type="stamp" n="TEST-DEV">TEST-DEV</idno>
            <idno type="stamp" n="TEST-HALCNRS">Collection test HAL CNRS</idno>
            <idno type="stamp" n="ENS-PSL" corresp="PSL">École normale supérieure - PSL</idno>
            <idno type="stamp" n="EPHE-PSL" corresp="PSL">École Pratique des Hautes Études - PSL</idno>
            <idno type="stamp" n="ESPCI-PSL" corresp="PSL">Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris - PSL</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="UM-2015-2021" corresp="UNIV-MONTPELLIER">Université de Montpellier (2015-2021)</idno>
            <idno type="stamp" n="TEST3-HALCNRS">TEST3-HALCNRS</idno>
            <idno type="stamp" n="TEST4-HALCNRS">collection test</idno>
            <idno type="stamp" n="TEST5-HALCNRS">collection test 5</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Machine Learning to Improve the Sensing of Biomolecules by Conical Track-Etched Nanopore</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Nathan</forename>
                    <surname>Meyer</surname>
                  </persName>
                  <email type="md5">e0858f9c9335a7eee659ca976ed5a18f</email>
                  <email type="domain">umontpellier.fr</email>
                  <idno type="idhal" notation="numeric">1547054</idno>
                  <idno type="halauthorid" notation="string">2064902-1547054</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=ch9dtl4AAAAJ</idno>
                  <affiliation ref="#struct-1087310"/>
                  <affiliation ref="#struct-1087121"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Marc</forename>
                    <surname>Janot</surname>
                  </persName>
                  <email type="md5">b8afe5e9acb70769d12b9193d3580df7</email>
                  <email type="domain">umontpellier.fr</email>
                  <idno type="idhal" notation="string">jean-marc-janot</idno>
                  <idno type="idhal" notation="numeric">16744</idno>
                  <idno type="halauthorid" notation="string">42965-16744</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/G-3217-2012</idno>
                  <idno type="IDREF">https://www.idref.fr/031208835</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0663-2995</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/G-3217-2012</idno>
                  <affiliation ref="#struct-1087310"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mathilde</forename>
                    <surname>Lepoitevin</surname>
                  </persName>
                  <email type="md5">078251d1f6b4d28067afef8b053965b0</email>
                  <email type="domain">brown.edu</email>
                  <idno type="idhal" notation="string">mathilde-lepoitevin</idno>
                  <idno type="idhal" notation="numeric">17221</idno>
                  <idno type="halauthorid" notation="string">17036-17221</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-0244-9939</idno>
                  <idno type="IDREF">https://www.idref.fr/225779811</idno>
                  <idno type="VIAF">https://viaf.org/viaf/457152636139220050455</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/D-1489-2016</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/D-1489-2016</idno>
                  <affiliation ref="#struct-522138"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Michael</forename>
                    <surname>Smietana</surname>
                  </persName>
                  <email type="md5">81ab955a8af90516401d7f8adf758f4a</email>
                  <email type="domain">umontpellier.fr</email>
                  <idno type="idhal" notation="string">michael-smietana</idno>
                  <idno type="idhal" notation="numeric">756205</idno>
                  <idno type="halauthorid" notation="string">132468-756205</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8132-7221</idno>
                  <idno type="IDREF">https://www.idref.fr/059806591</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/F-7828-2016</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=9yofNMEAAAAJ</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/F-7828-2016</idno>
                  <affiliation ref="#struct-24488"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Jacques</forename>
                    <surname>Vasseur</surname>
                  </persName>
                  <email type="md5">a09fe1c7c0bc71361d6718947b1ccb17</email>
                  <email type="domain">umontpellier.fr</email>
                  <idno type="idhal" notation="string">jean-jacques-vasseur</idno>
                  <idno type="idhal" notation="numeric">176784</idno>
                  <idno type="halauthorid" notation="string">125487-176784</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-4379-6139</idno>
                  <idno type="IDREF">https://www.idref.fr/068903847</idno>
                  <affiliation ref="#struct-24488"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Joan</forename>
                    <surname>Torrent</surname>
                  </persName>
                  <email type="md5">63d21716f01397cafc7ae35eeac628dd</email>
                  <email type="domain">univ-montp2.fr</email>
                  <idno type="idhal" notation="numeric">871775</idno>
                  <idno type="halauthorid" notation="string">468659-871775</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-6908-4084</idno>
                  <idno type="IDREF">https://www.idref.fr/24059391X</idno>
                  <idno type="VIAF">https://viaf.org/viaf/3593157583857133970007</idno>
                  <affiliation ref="#struct-1087121"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sebastien</forename>
                    <surname>Balme</surname>
                  </persName>
                  <email type="md5">aadc014d38c6e9587dcfb5f4d730a532</email>
                  <email type="domain">umontpellier.fr</email>
                  <idno type="idhal" notation="string">sbalme</idno>
                  <idno type="idhal" notation="numeric">16743</idno>
                  <idno type="halauthorid" notation="string">35976-16743</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-0779-3384</idno>
                  <idno type="IDREF">https://www.idref.fr/074013122</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8631-5334</idno>
                  <affiliation ref="#struct-1087310"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">11220</idno>
                <idno type="issn">0265-928X</idno>
                <title level="j">Biosensors</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">10</biblScope>
                  <biblScope unit="issue">10</biblScope>
                  <biblScope unit="pp">140</biblScope>
                  <date type="datePub">2020-10-05</date>
                  <date type="dateEpub">2020-09-30</date>
                </imprint>
              </monogr>
              <idno type="doi">10.3390/bios10100140</idno>
              <idno type="pubmed">33028025</idno>
              <idno type="pubmedcentral">PMC7601669</idno>
              <idno type="wos">000584175900001</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Nanopore</term>
                <term xml:lang="en">Machine learning</term>
                <term xml:lang="en">DNA sensing</term>
              </keywords>
              <classCode scheme="mesh">Biosensing Techniques</classCode>
              <classCode scheme="mesh">DNA</classCode>
              <classCode scheme="mesh">MAchine Learning</classCode>
              <classCode scheme="mesh">Nanopores</classCode>
              <classCode scheme="halDomain" n="chim.anal">Chemical Sciences/Analytical chemistry</classCode>
              <classCode scheme="halDomain" n="chim">Chemical Sciences</classCode>
              <classCode scheme="halDomain" n="chim.orga">Chemical Sciences/Organic chemistry</classCode>
              <classCode scheme="halDomain" n="chim.ther">Chemical Sciences/Medicinal Chemistry</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Single nanopore is a powerful platform to detect, discriminate and identify biomacromolecules. Among the different devices, the conical nanopores obtained by the track-etched technique on a polymer film are stable and easy to functionalize. However, these advantages are hampered by their high aspect ratio that avoids the discrimination of similar samples. Using machine learning, we demonstrate an improved resolution so that it can identify short single-and double-stranded DNA (10-and 40-mers). We have characterized each current blockade event by the relative intensity, dwell time, surface area and both the right and left slope. We show an overlap of the relative current blockade amplitudes and dwell time distributions that prevents their identification. We define the different parameters that characterize the events as features and the type of DNA sample as the target. By applying support-vector machines to discriminate each sample, we show accuracy between 50% and 72% by using two features that distinctly classify the data points. Finally, we achieved an increased accuracy (up to 82%) when five features were implemented.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-1087310" status="OLD">
          <idno type="ISNI">0000000121940104</idno>
          <idno type="RNSR">199412064U</idno>
          <idno type="ROR">https://ror.org/04nmj9827</idno>
          <orgName>Institut Européen des membranes</orgName>
          <orgName type="acronym">IEM</orgName>
          <date type="start">2015-01-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>1919, route de Mende - BP 5051 - 34293 Montpellier cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.iemm.univ-montp2.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300370" type="direct"/>
            <relation active="#struct-341038" type="direct"/>
            <relation active="#struct-410122" type="direct"/>
            <relation name="UMR5635" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1087121" status="OLD">
          <idno type="RNSR">200716389N</idno>
          <orgName>Mécanismes moléculaires dans les démences neurodégénératives</orgName>
          <orgName type="acronym">MMDN</orgName>
          <date type="start">2015-01-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>Place Eugène Bataillon 34095 Montpellier Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://mmdn.umontpellier.fr/fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-110691" type="direct"/>
            <relation active="#struct-564132" type="indirect"/>
            <relation name="U1198" active="#struct-303623" type="direct"/>
            <relation active="#struct-410122" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-522138" status="VALID">
          <idno type="IdRef">259394920</idno>
          <idno type="RNSR">201622206X</idno>
          <idno type="ROR">https://ror.org/04v668f18</idno>
          <orgName>Institut des Matériaux Poreux de Paris</orgName>
          <orgName type="acronym">IMAP</orgName>
          <date type="start">2016-09-01</date>
          <desc>
            <address>
              <addrLine>ENS, 24 rue Lhomond et ESPCI, 10 rue Vauquelin, 75005 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chimie.ens.fr/recherche/laboratoire-imap/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-240928" type="direct"/>
            <relation active="#struct-59704" type="indirect"/>
            <relation active="#struct-564132" type="indirect"/>
            <relation active="#struct-301585" type="direct"/>
            <relation active="#struct-341038" type="direct"/>
            <relation name="UMR8004 / FRE2000" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-24488" status="OLD">
          <idno type="RNSR">200711912X</idno>
          <idno type="ROR">https://ror.org/05d1e6v30</idno>
          <orgName>Institut des Biomolécules Max Mousseron [Pôle Chimie Balard]</orgName>
          <orgName type="acronym">IBMM</orgName>
          <date type="start">2006-01-01</date>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>Faculté de Pharmacie - 15 Av. Charles Flahault - BP 14 491 - 34093 Montpellier Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ibmm.univ-montp1.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300370" type="direct"/>
            <relation active="#struct-341038" type="direct"/>
            <relation active="#struct-410122" type="direct"/>
            <relation name="UMR5247" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300370" status="OLD">
          <idno type="ROR">https://ror.org/03sgyqj04</idno>
          <orgName>Ecole Nationale Supérieure de Chimie de Montpellier</orgName>
          <orgName type="acronym">ENSCM</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>8 Rue de l'Ecole Normale 34296 Montpellier Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.enscm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-341038" status="VALID">
          <idno type="IdRef">232435103</idno>
          <idno type="ISNI">000000010626358X</idno>
          <idno type="ROR">https://ror.org/02cte4b68</idno>
          <orgName>Institut de Chimie - CNRS Chimie</orgName>
          <orgName type="acronym">INC-CNRS</orgName>
          <date type="start">2009-10-01</date>
          <desc>
            <address>
              <addrLine>CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 rue Michel-Ange75794 PARIS CEDEX 16 - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cnrs.fr/inc</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-410122" status="OLD">
          <idno type="ISNI">0000000120970141</idno>
          <idno type="ROR">https://ror.org/051escj72</idno>
          <orgName>Université de Montpellier</orgName>
          <orgName type="acronym">UM</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>163 rue Auguste Broussonnet - 34090 Montpellier</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.umontpellier.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-110691" status="VALID">
          <idno type="IdRef">026375478</idno>
          <idno type="ISNI">0000000121955365</idno>
          <idno type="ROR">https://ror.org/046b3cj80</idno>
          <orgName>École Pratique des Hautes Études</orgName>
          <orgName type="acronym">EPHE</orgName>
          <date type="start">1868-01-01</date>
          <desc>
            <address>
              <addrLine>4-14 Rue Ferrus, 75014 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.ephe.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-564132" status="VALID">
          <idno type="IdRef">241597595</idno>
          <idno type="ISNI">0000 0004 1784 3645</idno>
          <idno type="ROR">https://ror.org/013cjyk83</idno>
          <orgName>Université Paris Sciences et Lettres</orgName>
          <orgName type="acronym">PSL</orgName>
          <desc>
            <address>
              <addrLine>60 rue Mazarine 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.psl.eu/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regrouplaboratory" xml:id="struct-240928" status="VALID">
          <idno type="IdRef">198500114</idno>
          <orgName>Département de Chimie - ENS-PSL</orgName>
          <date type="start">1985-01-01</date>
          <desc>
            <address>
              <addrLine>24 rue Lhomond75132 Paris Cedex 05</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chimie.ens.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-59704" type="direct"/>
            <relation active="#struct-564132" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-59704" status="VALID">
          <idno type="IdRef">031738419</idno>
          <idno type="ISNI">0000000123532622</idno>
          <idno type="ROR">https://ror.org/05a0dhs15</idno>
          <orgName>École normale supérieure - Paris</orgName>
          <orgName type="acronym">ENS-PSL</orgName>
          <date type="start">1985-07-24</date>
          <desc>
            <address>
              <addrLine>45, Rue d'Ulm - 75230 Paris cedex 05</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.ens.psl.eu/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301585" status="VALID">
          <idno type="IdRef">028114779</idno>
          <idno type="ISNI">000000009591493X</idno>
          <idno type="ROR">https://ror.org/03zx86w41</idno>
          <orgName>Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris</orgName>
          <orgName type="acronym">ESPCI Paris</orgName>
          <date type="start">1882-10-01</date>
          <desc>
            <address>
              <addrLine>10 rue Vauquelin, 75231 Paris cedex 05</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.espci.psl.eu/fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-53360" status="VALID">
          <idno type="anr">ANR-19-CE42-0006</idno>
          <orgName>NANOoligo</orgName>
          <desc>Nanopore Unique Pour L'analyse Précoces De L'agrégation de b-Amyloïde précurseur Maladie D'Alzheimer</desc>
          <date type="start">2019</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>