Textural, Structural and Biological Evaluation of Hydroxyapatite Doped with Zinc at Low Concentrations - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Materials Année : 2017

Textural, Structural and Biological Evaluation of Hydroxyapatite Doped with Zinc at Low Concentrations

Daniela Predoi
  • Fonction : Auteur
Simona Liliana Iconaru
  • Fonction : Auteur
  • PersonId : 1014910
Aurélien Deniaud
Mireille Chevallet
  • Fonction : Auteur
  • PersonId : 1079916
Nicolas Buton
  • Fonction : Auteur
  • PersonId : 1014912
Alina Mihaela Prodan
  • Fonction : Auteur
  • PersonId : 1014913

Résumé

The present work was focused on the synthesis and characterization of hydroxyapatite doped with low concentrations of zinc (Zn:HAp) (0.01 < x Zn < 0.05). The incorporation of low concentrations of Zn 2+ ions in the hydroxyapatite (HAp) structure was achieved by co-precipitation method. The physico-chemical properties of the samples were characterized by X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), Scanning Electron Microscopy (SEM), zeta-potential, and DLS and N 2-BET measurements. The results obtained by XRD and FTIR studies demonstrated that doping hydroxyapatite with low concentrations of zinc leads to the formation of a hexagonal structure with lattice parameters characteristic to hydroxyapatite. The XRD studies have also shown that the crystallite size and lattice parameters of the unit cell depend on the substitutions of Ca 2+ with Zn 2+ in the apatitic structure. Moreover, the FTIR analysis revealed that the water content increases with the increase of zinc concentration. Furthermore, the Energy Dispersive X-ray Analysis (EDAX) and XPS analyses showed that the elements Ca, P, O, and Zn were found in all the Zn:HAp samples suggesting that the synthesized materials were zinc doped hydroxyapatite, Ca 10−x Zn x (PO 4) 6 (OH), with 0.01 ≤ x Zn ≤ 0.05. Antimicrobial assays on Staphylococcus aureus and Escherichia coli bacterial strains and HepG2 cell viability assay were carried out.
Fichier principal
Vignette du fichier
Michaud-soretIsabelle_Predoi_2017.pdf (7.13 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02975694 , version 1 (22-10-2020)

Licence

Paternité

Identifiants

Citer

Daniela Predoi, Simona Liliana Iconaru, Aurélien Deniaud, Mireille Chevallet, Isabelle Michaud-Soret, et al.. Textural, Structural and Biological Evaluation of Hydroxyapatite Doped with Zinc at Low Concentrations. Materials, 2017, 10 (3), pp.229. ⟨10.3390/ma10030229⟩. ⟨hal-02975694⟩
92 Consultations
31 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More