The 3-PRS parallel manipulator with different arrangements of prismatic joints is called a reconfigurable 3-PRS parallel ma-nipulator in this paper. The three prismatic joints in PRS limbs are attached to the base with an angle α between the horizontal plane of the base and their directions. Based on [1], the manipu-lator has identical operation modes, namely x 0 = 0 and x 3 = 0 for any value of α. Accordingly, this paper presents in more details the performance evaluation of these operation modes by using the output transmission index (OTI) and the constraint transmission index (CTI). The OTI and CTI determine the force transmission efficiency and the constraining ability of the manipulators, respectively. Initially, the determination of the number and types of operation modes of the 3-PRS parallel manipulator is recalled. The computation is carried out by using an algebraic approach, namely the Study kinematic mapping. In each operation mode, the actuation wrenches and the constraint wrenches are obtained based on the Screw theory. Then, the OTI and CTI are traced in the orientation workspace of the manipulator for different values of angle α. Furthermore, the singularity conditions are analysed corresponding to the values of OTI and CTI.