Influence of common preanalytical variations on the metabolic profile of serum samples in biobanks - Archive ouverte HAL
Article Dans Une Revue Journal of Biomolecular NMR Année : 2011

Influence of common preanalytical variations on the metabolic profile of serum samples in biobanks

Résumé

A blood pre-centrifugation delay of 24 h at room temperature influenced the proton NMR spectroscopic profiles of human serum. A blood pre-centrifugation delay of 24 h at 4°C did not influence the spectroscopic profile as compared with 4 h delays at either room temperature or 4°C. Five or ten serum freeze-thaw cycles also influenced the proton NMR spectroscopic profiles. Certain common in vitro preanalytical variations occurring in biobanks may impact the metabolic profile of human serum.

Dates et versions

hal-02944594 , version 1 (21-09-2020)

Identifiants

Citer

Ophelie Fliniaux, Gwenaelle Gaillard, Antoine Lion, Dominique Cailleu, François Mesnard, et al.. Influence of common preanalytical variations on the metabolic profile of serum samples in biobanks. Journal of Biomolecular NMR, 2011, 51 (4), pp.457-465. ⟨10.1007/s10858-011-9574-5⟩. ⟨hal-02944594⟩
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