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Pré-Publication, Document De Travail (Preprint/Prepublication) Année : 2016

A clonally reproducing generalist aphid pest colonises diverse host plants by rapid transcriptional plasticity of duplicated gene clusters

Thomas Mathers
  • Fonction : Auteur
Yazhou Chen
  • Fonction : Auteur
Gemy Kaithakottil
  • Fonction : Auteur
Fabrice Legeai
Sam Mugford
  • Fonction : Auteur
Patrice Baa-Puyoulet
Anthony Bretaudeau
Bernardo Clavijo
  • Fonction : Auteur
Olivier Collin
Tamas Dalmay
  • Fonction : Auteur
Thomas Derrien
Honglin Feng
  • Fonction : Auteur
Toni Gabaldón
Anna Jordan
  • Fonction : Auteur
Irene Julca
  • Fonction : Auteur
Graeme Kettles
  • Fonction : Auteur
Krissana Kowitwanich
  • Fonction : Auteur
Dominique Lavenier
Paolo Lenzi
  • Fonction : Auteur
Sara Lopez-Gomollon
  • Fonction : Auteur
Damian Loska
  • Fonction : Auteur
Daniel Mapleson
  • Fonction : Auteur
Florian Maumus
Simon Moxon
  • Fonction : Auteur
Daniel Price
Akiko Sugio
Darren Waite
  • Fonction : Auteur
Georg Jander
  • Fonction : Auteur
Denis Tagu
Alex Wilson
  • Fonction : Auteur
Cock van Oosterhout
David Swarbreck
  • Fonction : Auteur
Saskia Hogenhout
  • Fonction : Auteur

Résumé

Background The prevailing paradigm of host-parasite evolution is that arms races lead to increasing specialisation via genetic adaptation. Insect herbivores are no exception, and the majority have evolved to colonise a small number of closely related host species. Remarkably, the green peach aphid, Myzus persicae , colonises plant species across 40 families and single M. persicae clonal lineages can colonise distantly related plants. This remarkable ability makes M. persicae a highly destructive pest of many important crop species. Results To investigate the exceptional phenotypic plasticity of M. persicae , we sequenced the M. persicae genome and assessed how one clonal lineage responds to host plant species of different families. We show that genetically identical individuals are able to colonise distantly related host species through the differential regulation of genes belonging to aphid-expanded gene families. Multigene clusters collectively up-regulate in single aphids within two days upon host switch. Furthermore, we demonstrate the functional significance of this rapid transcriptional change using RNA interference (RNAi)-mediated knock-down of genes belonging to the cathepsin B gene family. Knock-down of cathepsin B genes reduced aphid fitness, but only on the host that induced up-regulation of these genes. Conclusions Previous research has focused on the role of genetic adaptation of parasites to their hosts. Here we show that the generalist aphid pest M. persicae is able to colonise diverse host plant species in the absence of genetic specialisation. This is achieved through rapid transcriptional plasticity of genes that have duplicated during aphid evolution.

Dates et versions

hal-02936181 , version 1 (11-09-2020)

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Thomas Mathers, Yazhou Chen, Gemy Kaithakottil, Fabrice Legeai, Sam Mugford, et al.. A clonally reproducing generalist aphid pest colonises diverse host plants by rapid transcriptional plasticity of duplicated gene clusters. 2020. ⟨hal-02936181⟩
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