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Article Dans Une Revue BMC Microbiology Année : 2020

Characterization of mucosa-associated Escherichia coli strains isolated from Crohn’s disease patients in Brazil

Résumé

Crohn’s disease (CD) is characterized by chronic inflammation of the human intestine. Several studies have demonstrated that the intestinal mucosa of CD patients in Western countries is abnormally colonized by adherent-invasive Escherichia coli (AIEC) strains. However, no studies to date have focused on the involvement of such E. coli strains in CD patients in Brazil. Here, we characterized E. coli strains associated with the ileal mucosa of Brazilian CD patients (ileal biopsies from 35 subjects, 24 CD patients and 11 controls).

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hal-02903480 , version 1 (21-07-2020)

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Rafaella F. A. Costa, Maria L. A. Ferrari, Marie-Agnès Bringer, Arlette Darfeuille-Michaud, Flaviano S. Martins, et al.. Characterization of mucosa-associated Escherichia coli strains isolated from Crohn’s disease patients in Brazil. BMC Microbiology, 2020, 20 (1), pp.178. ⟨10.1186/s12866-020-01856-x⟩. ⟨hal-02903480⟩
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