<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-02870578</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-02T13:47:54+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Quantification of bis(2-ethylhexyl) phthalate released by medical devices during respiratory assistance and estimation of patient exposure</title>
            <author role="aut">
              <persName>
                <forename type="first">Yassine</forename>
                <surname>Bouattour</surname>
              </persName>
              <email type="md5">2a033eece50472e826d1e0a58c0fde2a</email>
              <email type="domain">hotmail.fr</email>
              <idno type="idhal" notation="string">yassine-bouattour</idno>
              <idno type="idhal" notation="numeric">180028</idno>
              <idno type="halauthorid" notation="string">2542024-180028</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-6937-1796</idno>
              <affiliation ref="#struct-490682"/>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mathieu</forename>
                <surname>Wasiak</surname>
              </persName>
              <idno type="halauthorid">1365239-0</idno>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Lise</forename>
                <surname>Bernard</surname>
              </persName>
              <email type="md5">e502bfe07760d91ba51d70948cc6d3b9</email>
              <email type="domain">uca.fr</email>
              <idno type="idhal" notation="string">lise-bernard</idno>
              <idno type="idhal" notation="numeric">180026</idno>
              <idno type="halauthorid" notation="string">47416-180026</idno>
              <idno type="IDREF">https://www.idref.fr/147973716</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1159-0048</idno>
              <affiliation ref="#struct-490682"/>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jérémy</forename>
                <surname>Pinguet</surname>
              </persName>
              <idno type="idhal" notation="numeric">1338794</idno>
              <idno type="halauthorid" notation="string">1190129-1338794</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6339-8392</idno>
              <idno type="IDREF">https://www.idref.fr/276000374</idno>
              <affiliation ref="#struct-491236"/>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Damien</forename>
                <forename type="middle">Richard</forename>
                <surname>Richard</surname>
              </persName>
              <idno type="halauthorid">25863-0</idno>
              <affiliation ref="#struct-491236"/>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mégane</forename>
                <surname>Le Rouzo-Grèves</surname>
              </persName>
              <idno type="halauthorid">1983815-0</idno>
              <affiliation ref="#struct-490682"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Imen</forename>
                <surname>Dhifallah</surname>
              </persName>
              <idno type="halauthorid">1983816-0</idno>
              <affiliation ref="#struct-490682"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Celine</forename>
                <surname>Lambert</surname>
              </persName>
              <idno type="halauthorid">1242449-0</idno>
              <affiliation ref="#struct-517230"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Bruno</forename>
                <surname>Pereira</surname>
              </persName>
              <idno type="halauthorid">726169-0</idno>
              <affiliation ref="#struct-517230"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">P.</forename>
                <surname>Chennell</surname>
              </persName>
              <email type="md5">198d8019cb195c2b507027ec5ee7a0a7</email>
              <email type="domain">uca.fr</email>
              <idno type="idhal" notation="string">philip-chennell</idno>
              <idno type="idhal" notation="numeric">180025</idno>
              <idno type="halauthorid" notation="string">35385-180025</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8086-7517</idno>
              <idno type="IDREF">https://www.idref.fr/174947348</idno>
              <affiliation ref="#struct-490682"/>
              <affiliation ref="#struct-300144"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Valérie</forename>
                <surname>Sautou</surname>
              </persName>
              <email type="md5">a1de23c861fc8e519e056e9f056c5010</email>
              <email type="domain">chu-clermontferrand.fr</email>
              <idno type="idhal" notation="string">valerie-sautou</idno>
              <idno type="idhal" notation="numeric">180029</idno>
              <idno type="halauthorid" notation="string">35379-180029</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-3944-3752</idno>
              <affiliation ref="#struct-490682"/>
              <affiliation ref="#struct-300144"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Accord Elsevier</forename>
                <surname>CCSD</surname>
              </persName>
              <email type="md5">3cc0cc7b8e3329bfb7423fa2578d788e</email>
              <email type="domain">ccsd.cnrs.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2022-05-20 11:29:14</date>
              <date type="whenModified">2025-04-28 17:14:23</date>
              <date type="whenReleased">2022-05-20 11:29:15</date>
              <date type="whenProduced">2020-09</date>
              <date type="whenEndEmbargoed">2021-05-14</date>
              <ref type="file" target="https://hal.science/hal-02870578v1/document">
                <date notBefore="2021-05-14"/>
              </ref>
              <ref type="file" subtype="author" n="1" target="https://hal.science/hal-02870578v1/file/S0045653520311711.pdf" id="file-3673849-3207761">
                <date notBefore="2021-05-14"/>
              </ref>
              <ref type="externalLink" target="https://www.sciencedirect.com/science/article/am/pii/S0045653520311711"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="1081876">
                <persName>
                  <forename>Accord Elsevier</forename>
                  <surname>CCSD</surname>
                </persName>
                <email type="md5">3cc0cc7b8e3329bfb7423fa2578d788e</email>
                <email type="domain">ccsd.cnrs.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-02870578</idno>
            <idno type="halUri">https://hal.science/hal-02870578</idno>
            <idno type="halBibtex">bouattour:hal-02870578</idno>
            <idno type="halRefHtml">&lt;i&gt;Chemosphere&lt;/i&gt;, 2020, 255, pp.126978. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.chemosphere.2020.126978"&gt;&amp;#x27E8;10.1016/j.chemosphere.2020.126978&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Chemosphere, 2020, 255, pp.126978. &amp;#x27E8;10.1016/j.chemosphere.2020.126978&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by-nc/4.0/">CC BY-NC 4.0 - Attribution - Non-commercial use<ref corresp="#file-3673849-3207761"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="PRES_CLERMONT">Université de Clermont</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="ICC" corresp="PRES_CLERMONT">Institut de Chimie de Clermont-Ferrand</idno>
            <idno type="stamp" n="ND" corresp="PRES_CLERMONT">Neuro-Dol</idno>
            <idno type="stamp" n="ACL-SVSAE" corresp="PRES_CLERMONT">ACL en SVSAE</idno>
            <idno type="stamp" n="ACL-SF" corresp="PRES_CLERMONT">ACL en Sciences fondamentales</idno>
            <idno type="stamp" n="INC-CNRS">Institut de Chimie du CNRS</idno>
            <idno type="stamp" n="CHU-CLERMONTFERRAND">CHU DE CLERMONT FERRAND</idno>
            <idno type="stamp" n="TEST-HALCNRS">Collection test HAL CNRS</idno>
            <idno type="stamp" n="ELSEVIER">Import Elsevier</idno>
            <idno type="stamp" n="CLERMONT-AUVERGNE-INP">Clermont Auvergne INP</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Quantification of bis(2-ethylhexyl) phthalate released by medical devices during respiratory assistance and estimation of patient exposure</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Yassine</forename>
                    <surname>Bouattour</surname>
                  </persName>
                  <email type="md5">2a033eece50472e826d1e0a58c0fde2a</email>
                  <email type="domain">hotmail.fr</email>
                  <idno type="idhal" notation="string">yassine-bouattour</idno>
                  <idno type="idhal" notation="numeric">180028</idno>
                  <idno type="halauthorid" notation="string">2542024-180028</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-6937-1796</idno>
                  <affiliation ref="#struct-490682"/>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mathieu</forename>
                    <surname>Wasiak</surname>
                  </persName>
                  <idno type="halauthorid">1365239-0</idno>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Lise</forename>
                    <surname>Bernard</surname>
                  </persName>
                  <email type="md5">e502bfe07760d91ba51d70948cc6d3b9</email>
                  <email type="domain">uca.fr</email>
                  <idno type="idhal" notation="string">lise-bernard</idno>
                  <idno type="idhal" notation="numeric">180026</idno>
                  <idno type="halauthorid" notation="string">47416-180026</idno>
                  <idno type="IDREF">https://www.idref.fr/147973716</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1159-0048</idno>
                  <affiliation ref="#struct-490682"/>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jérémy</forename>
                    <surname>Pinguet</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">1338794</idno>
                  <idno type="halauthorid" notation="string">1190129-1338794</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6339-8392</idno>
                  <idno type="IDREF">https://www.idref.fr/276000374</idno>
                  <affiliation ref="#struct-491236"/>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Damien</forename>
                    <forename type="middle">Richard</forename>
                    <surname>Richard</surname>
                  </persName>
                  <idno type="halauthorid">25863-0</idno>
                  <affiliation ref="#struct-491236"/>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mégane</forename>
                    <surname>Le Rouzo-Grèves</surname>
                  </persName>
                  <idno type="halauthorid">1983815-0</idno>
                  <affiliation ref="#struct-490682"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Imen</forename>
                    <surname>Dhifallah</surname>
                  </persName>
                  <idno type="halauthorid">1983816-0</idno>
                  <affiliation ref="#struct-490682"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Celine</forename>
                    <surname>Lambert</surname>
                  </persName>
                  <idno type="halauthorid">1242449-0</idno>
                  <affiliation ref="#struct-517230"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Bruno</forename>
                    <surname>Pereira</surname>
                  </persName>
                  <idno type="halauthorid">726169-0</idno>
                  <affiliation ref="#struct-517230"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">P.</forename>
                    <surname>Chennell</surname>
                  </persName>
                  <email type="md5">198d8019cb195c2b507027ec5ee7a0a7</email>
                  <email type="domain">uca.fr</email>
                  <idno type="idhal" notation="string">philip-chennell</idno>
                  <idno type="idhal" notation="numeric">180025</idno>
                  <idno type="halauthorid" notation="string">35385-180025</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8086-7517</idno>
                  <idno type="IDREF">https://www.idref.fr/174947348</idno>
                  <affiliation ref="#struct-490682"/>
                  <affiliation ref="#struct-300144"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Valérie</forename>
                    <surname>Sautou</surname>
                  </persName>
                  <email type="md5">a1de23c861fc8e519e056e9f056c5010</email>
                  <email type="domain">chu-clermontferrand.fr</email>
                  <idno type="idhal" notation="string">valerie-sautou</idno>
                  <idno type="idhal" notation="numeric">180029</idno>
                  <idno type="halauthorid" notation="string">35379-180029</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-3944-3752</idno>
                  <affiliation ref="#struct-490682"/>
                  <affiliation ref="#struct-300144"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">11643</idno>
                <idno type="issn">0045-6535</idno>
                <idno type="eissn">1879-1298</idno>
                <title level="j">Chemosphere</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">255</biblScope>
                  <biblScope unit="pp">126978</biblScope>
                  <date type="datePub">2020-09</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.chemosphere.2020.126978</idno>
              <idno type="pii">S0045-6535(20)31171-1</idno>
              <idno type="pubmed">32417514</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Respiratory assistance</term>
                <term xml:lang="en">bis(2-ethylhexyl) phthalate</term>
                <term xml:lang="en">ex vivo model</term>
                <term xml:lang="en">Respiratory</term>
                <term xml:lang="en">Polyvinyl chloride</term>
                <term xml:lang="en">Neonates</term>
                <term xml:lang="en">Medical devices</term>
              </keywords>
              <classCode scheme="halDomain" n="chim.mate">Chemical Sciences/Material chemistry</classCode>
              <classCode scheme="halDomain" n="sdv.ib.bio">Life Sciences [q-bio]/Bioengineering/Biomaterials</classCode>
              <classCode scheme="halDomain" n="sdv.sp.med">Life Sciences [q-bio]/Pharmaceutical sciences/Medication</classCode>
              <classCode scheme="halDomain" n="sdv.sp.pg">Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Bis(2-ethylhexyl) phthalate (DEHP) migration from polyvinyl chloride (PVC) has been studied with infusion, transfusion and extracorporeal oxygenation devices, but no study has been conducted to estimate its migration via respiratory medical devices (MDs). This work aims to develop an ex vivo model to quantify DEHP released doses by these MDs, which will then be used to estimate newborns DEHP exposure from respiratory assistance MDs. We followed the Frensh National Research and Safety Institute (INRS) recommendations for the validation of a collecting and analysing method of DEHP in air, which will be used to quantify DEHP in air passing through PVC respiratory assistance MDs. The developed method met all the validation criteria for DEHP determination in air. DEHP in air passing through MDs on the sixth day reached a cumulative quantity of 122.86 μg when using a flow rate of 4 L min-1 of non-humidified air while it was of 49.22 μg; 58.12 μg and 29.61 μg with flow rates of 2 L min-1 of humidified air, 2 L min-1 of dry air and 4 L min-1 of humidified air, respectively. Model application to two patients undergoing two different respiratory procedure demonstrated that noninvasive ventilation patient received higher dose of inhaled DEHP, confirmed by DEHP metabolites quantification in urine. Although the protective effect of air humidifiers on DEHP exposure was demonstrated, the effect of flow rate is difficult to be established. This developed method should be tested to verify its capacity to collect and quantify other plasticizers used in PVC MDs.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-490682" status="OLD">
          <idno type="IdRef">16450916X</idno>
          <idno type="ISNI">000000040582827X</idno>
          <idno type="RNSR">201220211W</idno>
          <idno type="ROR">https://ror.org/045qszf23</idno>
          <orgName>Institut de Chimie de Clermont-Ferrand</orgName>
          <orgName type="acronym">ICCF</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>Campus universitaire des Cézeaux, TSA 60026 - CS 60026, 24 avenue Blaise Pascal, 63178 Aubière</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://iccf.uca.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-322672" type="direct"/>
            <relation active="#struct-341038" type="direct"/>
            <relation name="UMR6296" active="#struct-422708" type="direct"/>
            <relation name="UMR6296" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300144" status="VALID">
          <idno type="IdRef">026606836</idno>
          <idno type="ISNI">0000000406394151</idno>
          <idno type="ROR">https://ror.org/02tcf7a68</idno>
          <orgName>CHU Clermont-Ferrand</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-491236" status="OLD">
          <idno type="IdRef">195779916</idno>
          <idno type="RNSR">201220182P</idno>
          <orgName>Neuro-Dol</orgName>
          <orgName type="acronym">Neuro-Dol</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>UFR Médecine Pharmacie, TSA 50400, 28 Place Henri Dunant, 63001 Clermont-Ferrand // Faculté de Chirurgie Dentaire, 2 Rue de Braga, 63100 Clermont-Ferrand</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://neurodol.uca.fr/</ref>
          </desc>
          <listRelation>
            <relation name="U1107" active="#struct-303623" type="direct"/>
            <relation name="UMR1107" active="#struct-422708" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-517230" status="VALID">
          <orgName>Service Biostatistiques, Télématiques, Traitement de l’image [CHU Clermont-Ferrand]</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/liste-services/biostatistiques-telematiques-traitement-de-limage</ref>
          </desc>
          <listRelation>
            <relation active="#struct-355679" type="direct"/>
            <relation active="#struct-300144" type="indirect"/>
            <relation active="#struct-1082766" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-322672" status="OLD">
          <orgName>SIGMA Clermont</orgName>
          <orgName type="acronym">SIGMA Clermont</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>SIGMA Clermont / Campus des Cézeaux  / CS 20265 / 63178 Aubière Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sigma-clermont.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-341038" status="VALID">
          <idno type="IdRef">232435103</idno>
          <idno type="ISNI">000000010626358X</idno>
          <idno type="ROR">https://ror.org/02cte4b68</idno>
          <orgName>Institut de Chimie - CNRS Chimie</orgName>
          <orgName type="acronym">INC-CNRS</orgName>
          <date type="start">2009-10-01</date>
          <desc>
            <address>
              <addrLine>CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE3 rue Michel-Ange75794 PARIS CEDEX 16 - France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cnrs.fr/inc</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-422708" status="OLD">
          <idno type="IdRef">196200032</idno>
          <idno type="ROR">https://ror.org/01a8ajp46</idno>
          <orgName>Université Clermont Auvergne [2017-2020]</orgName>
          <orgName type="acronym">UCA  [2017-2020]</orgName>
          <date type="start">2017-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>49, bd François-Mitterrand / CS 60032 / 63001 Clermont-Ferrand Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.uca.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-355679" status="VALID">
          <orgName>CHU Gabriel Montpied [Clermont-Ferrand]</orgName>
          <desc>
            <address>
              <addrLine>58 Rue Montalembert, 63000 Clermont-Ferrand</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/les-sites/site-gabriel-montpied</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300144" type="direct"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-1082766" status="VALID">
          <orgName>Pôle Santé Publique [CHU Clermont-Ferrand]</orgName>
          <desc>
            <address>
              <addrLine>CHU Clermont-Ferrand - Site Gabriel-Montpied, 58 Rue Montalembert, 63000 Clermont-Ferrand</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-clermontferrand.fr/liste-poles/pole-sante-publique</ref>
          </desc>
          <listRelation>
            <relation active="#struct-355679" type="direct"/>
            <relation active="#struct-300144" type="indirect"/>
          </listRelation>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>