Impact of micronutrient dietary intake and status on intestinal zinc absorption in late middle-aged men: The ZENITH study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue European Journal of Clinical Nutrition Année : 2005

Impact of micronutrient dietary intake and status on intestinal zinc absorption in late middle-aged men: The ZENITH study

S.J. Coulter
  • Fonction : Auteur

Résumé

BACKGROUND: Adjustments in intestinal absorption and losses of zinc (Zn) are thought to maintain Zn homeostasis when dietary intake levels are altered. Zn status may also influence efficiency of intestinal Zn absorption. OBJECTIVES: To determine the impact of dietary intake and status of some micronutrients on Zn absorption in late middle-aged men. DESIGN AND PARTICIPANTS: Dietary intake and status of Zn, Cu, Fe, vitamin A, C and fibre, and absorption of Zn were measured in 48 men, aged 58-68 y, confined to a metabolic unit and consuming a typical French diet. Dietary intake was estimated using 4-day food-intake records (including the weekend) and the GENI program. To assess Zn status, serum, erythrocyte, urine Zn levels and serum alkaline phosphatase activity were determined. Zn absorption was determined using the isotope double-labelling method. Zn stable isotopic ratios were measured in plasma samples collected before and 48 h after isotope administration using ICP/MS. RESULTS: Zn intake within the group of men varied from 5.7 to 20.5 mg/day and averaged 12.9 mg/day. Serum Zn level varied from 10 to 18 micromol/l and averaged 12.9 micromol/l. Zn absorption varied from 12 to 46% and averaged 29.7%. Zn absorption was not significantly (P > 0.05) correlated with Zn intake or with any of the Zn status parameters. Zn absorption was only slightly negatively correlated with serum and erythrocyte Zn levels and with serum Fe and ferritin levels in this study. CONCLUSION: Zn dietary intake and Zn absorption were satisfactory and led to an adequate Zn status in this population.

Dates et versions

hal-02683191 , version 1 (01-06-2020)

Identifiants

Citer

Nathalie Meunier, Christine Feillet Coudray, Mathieu Rambeau, Maud Andriollo-Sanchez, Marion Brandolini-Bunlon, et al.. Impact of micronutrient dietary intake and status on intestinal zinc absorption in late middle-aged men: The ZENITH study. European Journal of Clinical Nutrition, 2005, 59 (suppl. 2), pp.S48-S52. ⟨10.1038/sj.ejcn.1602298⟩. ⟨hal-02683191⟩
17 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More