<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-02637675</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-14T14:29:21+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7</title>
            <author role="aut">
              <persName>
                <forename type="first">Emiko</forename>
                <surname>Uchikawa</surname>
              </persName>
              <idno type="halauthorid">990269-0</idno>
              <affiliation ref="#struct-1047"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Kundhavai S.</forename>
                <surname>Natchiar</surname>
              </persName>
              <email type="md5">b048de7c6f09597d73d26db6be005238</email>
              <email type="domain">unistra.fr</email>
              <idno type="idhal" notation="numeric">1134927</idno>
              <idno type="halauthorid" notation="string">1885080-1134927</idno>
              <affiliation ref="#struct-1047"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Xiao</forename>
                <surname>Han</surname>
              </persName>
              <email type="md5">4d234e1894effce1904cbf318ccb8782</email>
              <email type="domain">it-sudparis.eu</email>
              <idno type="idhal" notation="numeric">934513</idno>
              <idno type="halauthorid" notation="string">570473-934513</idno>
              <affiliation ref="#struct-59704"/>
              <affiliation ref="#struct-499189"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Florence</forename>
                <surname>Proux</surname>
              </persName>
              <idno type="halauthorid">305297-0</idno>
              <affiliation ref="#struct-59704"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pierre</forename>
                <surname>Roblin</surname>
              </persName>
              <idno type="halauthorid">505397-0</idno>
              <affiliation ref="#struct-87540"/>
              <affiliation ref="#struct-1744"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Elodie</forename>
                <surname>Zhang</surname>
              </persName>
              <idno type="halauthorid">1614623-0</idno>
              <affiliation ref="#struct-59704"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alexandre</forename>
                <surname>Durand</surname>
              </persName>
              <email type="md5">c9dba4a6a51d3f3d4dd38b8e20bef8b9</email>
              <email type="domain">igbmc.fr</email>
              <idno type="idhal" notation="numeric">949580</idno>
              <idno type="halauthorid" notation="string">785103-949580</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-9173-6886</idno>
              <idno type="IDREF">https://www.idref.fr/189479809</idno>
              <affiliation ref="#struct-1047"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Bruno</forename>
                <forename type="middle">P.</forename>
                <surname>Klaholz</surname>
              </persName>
              <email type="md5">6011d8d4798176b09e015d52380aeda3</email>
              <email type="domain">igbmc.u-strasbg.fr</email>
              <idno type="idhal" notation="string">bruno-klaholz</idno>
              <idno type="idhal" notation="numeric">1022624</idno>
              <idno type="halauthorid" notation="string">418034-1022624</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-8674-8674</idno>
              <idno type="IDREF">https://www.idref.fr/148649653</idno>
              <affiliation ref="#struct-1047"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">Anne-Catherine</forename>
                <surname>Dock-Bregeon</surname>
              </persName>
              <email type="md5">4ac21e4ebd1ab5e116a95ef3356a184e</email>
              <email type="domain">sb-roscoff.fr</email>
              <idno type="idhal" notation="numeric">1233916</idno>
              <idno type="halauthorid" notation="string">242005-1233916</idno>
              <idno type="IDREF">https://www.idref.fr/033702640</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-6913-4061</idno>
              <affiliation ref="#struct-59704"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Migration</forename>
                <surname>ProdInra</surname>
              </persName>
              <email type="md5">9e5ed7d56b52b3d4383123b1ffb42236</email>
              <email type="domain">inrae.fr</email>
            </editor>
            <funder ref="#projanr-47679"/>
            <funder ref="#projanr-1188"/>
            <funder ref="#projanr-35426"/>
            <funder ref="#projanr-49738"/>
            <funder ref="#projanr-50581"/>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2020-05-27 23:46:32</date>
              <date type="whenModified">2026-02-03 10:31:59</date>
              <date type="whenReleased">2020-05-27 23:46:36</date>
              <date type="whenProduced">2015</date>
              <date type="whenEndEmbargoed">2020-05-27</date>
              <ref type="file" target="https://hal.inrae.fr/hal-02637675v1/document">
                <date notBefore="2020-05-27"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://hal.inrae.fr/hal-02637675v1/file/2015_Uchikawa_Nucleic%20Acids%20Research_1.pdf" id="file-2637675-2462189">
                <date notBefore="2020-05-27"/>
              </ref>
              <ref type="externalLink" target="https://academic.oup.com/nar/article-pdf/43/6/3373/17435125/gkv173.pdf"/>
              <fs>
                <f name="inra_etatDocument_local" notation="string" n="VE">
                  <string>inra_etatDocument_local_VE</string>
                </f>
                <f name="inra_publicVise_local" notation="string" n="SC">
                  <string>inra_publicVise_local_SC</string>
                </f>
              </fs>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="888556">
                <persName>
                  <forename>Migration</forename>
                  <surname>ProdInra</surname>
                </persName>
                <email type="md5">9e5ed7d56b52b3d4383123b1ffb42236</email>
                <email type="domain">inrae.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-02637675</idno>
            <idno type="halUri">https://hal.inrae.fr/hal-02637675</idno>
            <idno type="halBibtex">uchikawa:hal-02637675</idno>
            <idno type="halRefHtml">&lt;i&gt;Nucleic Acids Research&lt;/i&gt;, 2015, 43 (6), pp.3373 - 3388. &lt;a target="_blank" href="https://dx.doi.org/10.1093/nar/gkv173"&gt;&amp;#x27E8;10.1093/nar/gkv173&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Nucleic Acids Research, 2015, 43 (6), pp.3373 - 3388. &amp;#x27E8;10.1093/nar/gkv173&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by-nc/4.0/">CC BY-NC 4.0 - Attribution - Non-commercial use<ref corresp="#file-2637675-2462189"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="ENS-PARIS">Ecole Normale Supérieure de Paris</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-STRASBG1">Université Louis Pasteur - Strasbourg I</idno>
            <idno type="stamp" n="IGBMC" corresp="INSERM">Institut Génétique de Biologie Moléculaire et Cellulaire</idno>
            <idno type="stamp" n="INRA">INRA - Institut national de la recherche agronomique</idno>
            <idno type="stamp" n="UNIV-STRASBG">Université de Strasbourg</idno>
            <idno type="stamp" n="GIP-BE">GIP Bretagne Environnement</idno>
            <idno type="stamp" n="PSL">Université Paris sciences et lettres</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="SYNCHROTRON-SOLEIL">Synchrotron Soleil</idno>
            <idno type="stamp" n="SITE-ALSACE">Archive ouverte du site Alsace</idno>
            <idno type="stamp" n="AMIDEX">AMIDEX</idno>
            <idno type="stamp" n="INRAE">Institut National de Recherche en Agriculture, Alimentation et Environnement</idno>
            <idno type="stamp" n="ENS-PSL" corresp="PSL">École normale supérieure - PSL</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="GS-PHYSIQUE">Graduate School Physique</idno>
            <idno type="stamp" n="INSTITUT-SCIENCES-LUMIERE">Institut des Sciences de la Lumière</idno>
            <idno type="stamp" n="UNIVOAK">UNIVOAK</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Emiko</forename>
                    <surname>Uchikawa</surname>
                  </persName>
                  <idno type="halauthorid">990269-0</idno>
                  <affiliation ref="#struct-1047"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Kundhavai S.</forename>
                    <surname>Natchiar</surname>
                  </persName>
                  <email type="md5">b048de7c6f09597d73d26db6be005238</email>
                  <email type="domain">unistra.fr</email>
                  <idno type="idhal" notation="numeric">1134927</idno>
                  <idno type="halauthorid" notation="string">1885080-1134927</idno>
                  <affiliation ref="#struct-1047"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Xiao</forename>
                    <surname>Han</surname>
                  </persName>
                  <email type="md5">4d234e1894effce1904cbf318ccb8782</email>
                  <email type="domain">it-sudparis.eu</email>
                  <idno type="idhal" notation="numeric">934513</idno>
                  <idno type="halauthorid" notation="string">570473-934513</idno>
                  <affiliation ref="#struct-59704"/>
                  <affiliation ref="#struct-499189"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Florence</forename>
                    <surname>Proux</surname>
                  </persName>
                  <idno type="halauthorid">305297-0</idno>
                  <affiliation ref="#struct-59704"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pierre</forename>
                    <surname>Roblin</surname>
                  </persName>
                  <idno type="halauthorid">505397-0</idno>
                  <affiliation ref="#struct-87540"/>
                  <affiliation ref="#struct-1744"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Elodie</forename>
                    <surname>Zhang</surname>
                  </persName>
                  <idno type="halauthorid">1614623-0</idno>
                  <affiliation ref="#struct-59704"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alexandre</forename>
                    <surname>Durand</surname>
                  </persName>
                  <email type="md5">c9dba4a6a51d3f3d4dd38b8e20bef8b9</email>
                  <email type="domain">igbmc.fr</email>
                  <idno type="idhal" notation="numeric">949580</idno>
                  <idno type="halauthorid" notation="string">785103-949580</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-9173-6886</idno>
                  <idno type="IDREF">https://www.idref.fr/189479809</idno>
                  <affiliation ref="#struct-1047"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Bruno</forename>
                    <forename type="middle">P.</forename>
                    <surname>Klaholz</surname>
                  </persName>
                  <email type="md5">6011d8d4798176b09e015d52380aeda3</email>
                  <email type="domain">igbmc.u-strasbg.fr</email>
                  <idno type="idhal" notation="string">bruno-klaholz</idno>
                  <idno type="idhal" notation="numeric">1022624</idno>
                  <idno type="halauthorid" notation="string">418034-1022624</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-8674-8674</idno>
                  <idno type="IDREF">https://www.idref.fr/148649653</idno>
                  <affiliation ref="#struct-1047"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">Anne-Catherine</forename>
                    <surname>Dock-Bregeon</surname>
                  </persName>
                  <email type="md5">4ac21e4ebd1ab5e116a95ef3356a184e</email>
                  <email type="domain">sb-roscoff.fr</email>
                  <idno type="idhal" notation="numeric">1233916</idno>
                  <idno type="halauthorid" notation="string">242005-1233916</idno>
                  <idno type="IDREF">https://www.idref.fr/033702640</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-6913-4061</idno>
                  <affiliation ref="#struct-59704"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">1850</idno>
                <idno type="issn">0305-1048</idno>
                <idno type="eissn">1362-4962</idno>
                <title level="j">Nucleic Acids Research</title>
                <imprint>
                  <publisher>Oxford University Press</publisher>
                  <biblScope unit="volume">43</biblScope>
                  <biblScope unit="issue">6</biblScope>
                  <biblScope unit="pp">3373 - 3388</biblScope>
                  <date type="datePub">2015</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1093/nar/gkv173</idno>
              <idno type="prodinra">340153</idno>
              <idno type="pubmed">25753663</idno>
              <idno type="wos">000354719300038</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="halDomain" n="sdv.ot">Life Sciences [q-bio]/Other [q-bio.OT]</classCode>
              <classCode scheme="vocinrae-old" n="stabilisation chimique">stabilisation chimique</classCode>
              <classCode scheme="vocinrae-old" n="relation structure fonction">relation structure fonction</classCode>
              <classCode scheme="vocinrae-old" n="ribonucléoprotéine">ribonucléoprotéine</classCode>
              <classCode scheme="vocinrae-old" n="structure moléculaire">structure moléculaire</classCode>
              <classCode scheme="vocinrae-old" n="arn">arn</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>The non-coding RNA 7SK is the scaffold for a small nuclear ribonucleoprotein (7SKsnRNP) which regulates the function of the positive transcription elongation factor P-TEFb in the control of RNA polymerase II elongation in metazoans. The La-related protein LARP7 is a component of the 7SKsnRNP required for stability and function of the RNA. To address the function of LARP7 we determined the crystal structure of its La module, which binds a stretch of uridines at the 3'-end of 7SK. The structure shows that the penultimate uridine is tethered by the two domains, the La-motif and the RNA-recognition motif (RRM1), and reveals that the RRM1 is significantly smaller and more exposed than in the La protein. Sequence analysis suggests that this impacts interaction with 7SK. Binding assays, footprinting and small-angle scattering experiments show that a second RRM domain located at the C-terminus binds the apical loop of the 3' hairpin of 7SK, while the N-terminal domains bind at its foot. Our results suggest that LARP7 uses both its N- and C-terminal domains to stabilize 7SK in a closed structure, which forms by joining conserved sequences at the 5'-end with the foot of the 3' hairpin and has thus functional implications.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-1047" status="OLD">
          <orgName>Institut de génétique et biologie moléculaire et cellulaire</orgName>
          <orgName type="acronym">IGBMC</orgName>
          <date type="end">2008-12-31</date>
          <desc>
            <address>
              <addrLine>I.G.B.M.C, Parc D'Innovation 1 Rue Laurent Fries - BP 10142 67404 ILLKIRCH CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www-ulp.u-strasbg.fr/unite_recherche.php?u=14</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300320" type="direct"/>
            <relation name="U596" active="#struct-303623" type="direct"/>
            <relation name="UMR7104" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-59704" status="VALID">
          <idno type="IdRef">031738419</idno>
          <idno type="ISNI">0000000123532622</idno>
          <idno type="ROR">https://ror.org/05a0dhs15</idno>
          <orgName>École normale supérieure - Paris</orgName>
          <orgName type="acronym">ENS-PSL</orgName>
          <date type="start">1985-07-24</date>
          <desc>
            <address>
              <addrLine>45, Rue d'Ulm - 75230 Paris cedex 05</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.ens.psl.eu/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-564132" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-499189" status="INCOMING">
          <orgName>East China Normal University</orgName>
          <desc>
            <address>
              <country key="CN"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-87540" status="OLD">
          <orgName>Département Caractérisation et Elaboration des Produits Issus de l'Agriculture</orgName>
          <orgName type="acronym">CEPIA</orgName>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Rue de la Géraudière B.P. 71627, 44316 Nantes Cedex 3</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.cepia.inra.fr</ref>
          </desc>
          <listRelation>
            <relation name="UAR1008" active="#struct-92114" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1744" status="VALID">
          <idno type="RNSR">200119741H</idno>
          <idno type="ROR">https://ror.org/01ydb3330</idno>
          <orgName>Synchrotron SOLEIL</orgName>
          <orgName type="acronym">SSOLEIL</orgName>
          <desc>
            <address>
              <addrLine>L'Orme des Merisiers Saint-Aubin - BP 48 91192 GIF-sur-YVETTE CEDEX</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.synchrotron-soleil.fr</ref>
          </desc>
          <listRelation>
            <relation name="UR1" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300320" status="OLD">
          <orgName>Université Louis Pasteur - Strasbourg I</orgName>
          <date type="start">1970-01-01</date>
          <date type="end">2009-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-564132" status="VALID">
          <idno type="IdRef">241597595</idno>
          <idno type="ISNI">0000 0004 1784 3645</idno>
          <idno type="ROR">https://ror.org/013cjyk83</idno>
          <orgName>Université Paris Sciences et Lettres</orgName>
          <orgName type="acronym">PSL</orgName>
          <desc>
            <address>
              <addrLine>60 rue Mazarine 75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.psl.eu/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-92114" status="OLD">
          <idno type="ROR">https://ror.org/01x3gbx83</idno>
          <orgName>Institut National de la Recherche Agronomique</orgName>
          <orgName type="acronym">INRA</orgName>
          <date type="start">1946-05-18</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inra.fr</ref>
          </desc>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-47679" status="VALID">
          <idno type="anr">ANR-11-IDEX-0001</idno>
          <orgName>Amidex</orgName>
          <desc>INITIATIVE D'EXCELLENCE AIX MARSEILLE UNIVERSITE</desc>
          <date type="start">2011</date>
        </org>
        <org type="anrProject" xml:id="projanr-1188" status="VALID">
          <idno type="anr">ANR-06-BLAN-0072</idno>
          <idno type="program">Programme "blanc"</idno>
          <orgName>TrscrREGsnRNP</orgName>
          <desc>ETUDES STRUCTURALES ET FONCTIONNELLES DE snRNP REGULATRICES DE LA TRANSCRIPTION</desc>
          <date type="start">2006</date>
        </org>
        <org type="anrProject" xml:id="projanr-35426" status="VALID">
          <idno type="anr">ANR-12-BSV5-0018</idno>
          <idno type="program">BLANC</idno>
          <orgName>DynamIC</orgName>
          <desc>Dynamique et interactions de complexes intranucléaires par microscopie.</desc>
          <date type="start">2012</date>
        </org>
        <org type="anrProject" xml:id="projanr-49738" status="VALID">
          <idno type="anr">ANR-10-LABX-0054</idno>
          <orgName>MEMOLIFE</orgName>
          <desc>Memory in living systems: an integrated approach</desc>
          <date type="start">2010</date>
        </org>
        <org type="anrProject" xml:id="projanr-50581" status="VALID">
          <idno type="anr">ANR-10-INBS-0005</idno>
          <orgName>FRISBI</orgName>
          <desc>Infrastructure Française pour la Biologie Structurale Intégrée</desc>
          <date type="start">2010</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>