Functional redundancy and ecological innovation shape the circulation of tick-transmitted pathogens - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Frontiers in Cellular and Infection Microbiology Année : 2017

Functional redundancy and ecological innovation shape the circulation of tick-transmitted pathogens

Résumé

Ticks are vectors of pathogens affecting human and animal health worldwide. Nevertheless, the ecological and evolutionary interactions between ticks, hosts, and pathogens are largely unknown. Here, we integrated a framework to evaluate the associations of the tick Ixodes ricinus with its hosts and environmental niches that impact pathogen circulation. The analysis of tick-hosts association suggested that mammals and lizards were the ancestral hosts of this tick species, and that a leap to Aves occurred around 120 M years ago. The signature of the environmental variables over the host’s phylogeny revealed the existence of two clades of vertebrates diverging along a temperature and vegetation split. This is a robust proof that the tick probably experienced a colonization of new niches by adapting to a large set of new hosts, Aves. Interestingly, the colonization of Aves as hosts did not increase significantly the ecological niche of I. ricinus, but remarkably Aves are super-spreaders of pathogens. The disparate contribution of Aves to the tick-host-pathogen networks revealed that I. ricinus evolved to maximize habitat overlap with some hosts that are super-spreaders of pathogens. These results supported the hypothesis that large host networks are not a requirement of tick survival but pathogen circulation. The biological cost of tick adaptation to non-optimal environmental conditions might be balanced by molecular me chanisms triggered by the pathogens that we have only begun to understand.
Fichier principal
Vignette du fichier
2017_Estrada-Pena_Front Cell Infect Microbiol_1.pdf (1.71 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02627139 , version 1 (26-05-2020)

Licence

Paternité

Identifiants

Citer

Agustin Estrada-Peña, José de La Fuente, Alejandro Cabezas Cruz. Functional redundancy and ecological innovation shape the circulation of tick-transmitted pathogens. Frontiers in Cellular and Infection Microbiology, 2017, 7 (234), ⟨10.3389/fcimb.2017.00234⟩. ⟨hal-02627139⟩
53 Consultations
16 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More