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Article Dans Une Revue Journal de Gynécologie Obstétrique et Biologie de la Reproduction Année : 2014

Chronic maternal diseases and pregnancy losses. French guidelines

Pathologies maternelles chroniques et pertes de grossesse. Recommandations françaises

Résumé

Aim.-To review the available data on maternal chronic diseases and pregnancy losses.Material and Methods-We searched PubMed and the Cochrane library with pregnancy loss,stillbirth, intrauterine fetal demise, intrauterine fetal death, miscarriage and each maternaldiseases of this paper.Results-Antiphospholipid antibodies (anticardiolipin, anti-beta-2-glycoprotein, lupus anti-coagulant) should be measured in case of miscarriage after 10 WG confirmed by ultrasound(grade B) and an antiphospholipid syndrome should be treated by a combination of aspi-rin and low-molecular-weight heparin during a subsequent pregnancy (grade A). We donot recommend testing for genetic thrombophilia in case of first trimester miscarriage(grade B) or stillbirth (grade C). Glycemic control should be a goal before pregnancyfor women with pregestational diabetes to limit the risks of pregnancy loss (grade A)with a goal of prepregnancy HbA1c < 7%. Overt and subclinical hypothyroidisms should betreated by L-thyroxin during pregnancy to reduce the risks of pregnancy loss (grade A).Women who are positive for TPOAb should have TSH concentrations follow-up during pre-gnancy and subsequently treated by L-thyroxin if they develop subclinical hypothyroidism(grade B).Conclusions.-Prepregnancy management of most chronic maternal diseases, ideally throughprepregnancy multidisciplinary counseling, reduces the risks of pregnancy loss.
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Dates et versions

hal-02573728 , version 1 (14-05-2020)

Identifiants

  • HAL Id : hal-02573728 , version 1
  • PUBMED : 25447366

Citer

Jacky Nizard, Gaëlle Guettrot-Imbert, Geneviève Plu-Bureau, Cécile A. Ciangura, Sophie Jacqueminet, et al.. Pathologies maternelles chroniques et pertes de grossesse. Recommandations françaises. Journal de Gynécologie Obstétrique et Biologie de la Reproduction, 2014, 43 (10), pp.865-882. ⟨hal-02573728⟩
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