Article Dans Une Revue Antimicrobial Agents and Chemotherapy Année : 2015

K13-Propeller Polymorphisms in Plasmodium falciparum Isolates from Patients in Mayotte in 2013 and 2014

Résumé

Plasmodium falciparum isolates were collected from 29 malaria patients treated with artemether-lumefantrine in Mayotte in 2013 and 2014. Twenty-four cases (83%) consisted of imported malaria. Seventeen percent of the isolates presented mutations in one of the six K13-propeller blades (N490H, F495L, N554H/K, and E596G). A total of 23.8% of the isolates from the Union of Comoros showed K13-propeller polymorphisms. Three of the 18 isolates (16.7%) from Grande Comore showed polymorphisms (N490H, N554K, and E596G).

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hal-02560640 , version 1 (06-11-2024)

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Marylin Torrentino-Madamet, Louis Collet, Jean François Lepère, Nicolas Benoit, Remy Amalvict, et al.. K13-Propeller Polymorphisms in Plasmodium falciparum Isolates from Patients in Mayotte in 2013 and 2014. Antimicrobial Agents and Chemotherapy, 2015, 59 (12), pp.7878-7881. ⟨10.1128/AAC.01251-15⟩. ⟨hal-02560640⟩
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