LecB, a High Affinity Soluble Fucose-Binding Lectin from Pseudomonas aeruginosa - Archive ouverte HAL
Article Dans Une Revue Methods in Molecular Biology Année : 2020

LecB, a High Affinity Soluble Fucose-Binding Lectin from Pseudomonas aeruginosa

Résumé

LecB/PA-IIL (Pfam PF07472) from bacterium Pseudomonas aeruginosa is a fucose-binding lectin with unusual high affinity for glycans. The occurrence of LecB and related proteins is limited to few opportunistic bacterial species, some of them being responsible for severe infections in immune compromised patients. This lectin is therefore of interest as a target for the design of anti-infectious compounds, but can also be used for research and biotechnology. LecB is a small protein that can be produced in good quantity in recombinant system and purified by affinity chromatography.
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Dates et versions

hal-02554312 , version 1 (25-04-2020)

Identifiants

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Émilie Gillon, Annabelle Varrot, Anne Imberty. LecB, a High Affinity Soluble Fucose-Binding Lectin from Pseudomonas aeruginosa. Methods in Molecular Biology, 2020, Lectin purification and analysis (2132), pp.475-482. ⟨10.1007/978-1-0716-0430-4_46⟩. ⟨hal-02554312⟩
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