Major problems worldwide are environmental concern and energy shortage along with the high consumption of energy in buildings and the lack of sources. Buildings are the most intensive energy consumers, and account for 40% of worldwide energy use, which is much more than transportation. In next 25 years, CO2 emissions from buildings are projected to grow faster than in other sectors. Thus, architects must attempt to find solutions for managing buildings energy consumption. One of new innovative approaches is Biomimicry, which is defined as the applied science that derives inspiration for solutions to human problems through the study of natural designs’ principles. Although biomimicry is considered to be a new approach for achieving sustainable architecture, but there is still not enough access for architects to make use of it, especially to implement biomimetic design strategy in architectural project. The main objective of this paper is to raise awareness of architects making use of biomimetic strategies with better accessible facility. We propose to create the tool setting relationship to formalize and bridge between biological and architectural knowledge, along with investigative tools to investigate the ability of reducing energy consumption by applying the biomimetic strategies on efficient-energy building design. This article hypothetically proposes an investigative tool based on Bayesian networks for testing the rapid result of choices from natural devices according to specific multi-criteria requirements in each case study.