The paper presents the overview and comparative analysis of landscape cross-cultural and sub-cultural perception research methodologies in order to develop hypothetical methodological framework of interdisciplinary evaluation of cultural differences in landscape perception. The landscape research methods used for the analysis of impact of socio-cultural factors on landscape perception can be classified as mix of psychophysical and cognitive approach and are mostly based on the statistical analysis of the results of sociological research. Drawing the research closer to the relational concept, we propose the hypothetical methodological scheme of interdisciplinary evaluation of cultural differences in landscape perception that integrates landscape research with the knowledge of cultural studies, quantitative sociology (statistical analysis of the results of sociological research: factor analysis, component analysis, correlations, etc.), environmental psychology (cognitive mapping, Landscape Image Sketching Technique, landscape and environmental preferences, way finding, eye-tracking, etc.), and geography (geomatic) (geographic information systems, remote sensing).