<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-02532029</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-22T09:01:25+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Is biological randomness a statistical physics concept?</title>
            <author role="aut">
              <persName>
                <forename type="first">Ovidiu</forename>
                <surname>Radulescu</surname>
              </persName>
              <email type="md5">5e6c2ac6e5af23359597262493d7302d</email>
              <email type="domain">umontpellier.fr</email>
              <idno type="idhal" notation="string">ovidiu-radulescu</idno>
              <idno type="idhal" notation="numeric">740482</idno>
              <idno type="halauthorid" notation="string">3670-740482</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-6453-5707</idno>
              <idno type="IDREF">https://www.idref.fr/137807074</idno>
              <affiliation ref="#struct-410122"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Adrian</forename>
                <surname>Devenyi</surname>
              </persName>
              <idno type="halauthorid">1819035-0</idno>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Ovidiu</forename>
                <surname>Radulescu</surname>
              </persName>
              <email type="md5">5e6c2ac6e5af23359597262493d7302d</email>
              <email type="domain">umontpellier.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2020-04-08 15:42:05</date>
              <date type="whenModified">2022-08-05 10:48:54</date>
              <date type="whenReleased">2020-04-08 15:53:11</date>
              <date type="whenProduced">2019-10-07</date>
              <date type="whenEndEmbargoed">2020-04-04</date>
              <ref type="file" target="https://hal.science/hal-02532029v1/document">
                <date notBefore="2020-04-04"/>
              </ref>
              <ref type="file" subtype="publisherAgreement" n="1" target="https://hal.science/hal-02532029v1/file/Is_biological_randomness_a_statistical_physics_concept_%281%29.pdf" id="file-2532029-2405914">
                <date notBefore="2020-04-04"/>
              </ref>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="16775">
                <persName>
                  <forename>Ovidiu</forename>
                  <surname>Radulescu</surname>
                </persName>
                <email type="md5">5e6c2ac6e5af23359597262493d7302d</email>
                <email type="domain">umontpellier.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-02532029</idno>
            <idno type="halUri">https://hal.science/hal-02532029</idno>
            <idno type="halBibtex">radulescu:hal-02532029</idno>
            <idno type="halRefHtml">&lt;i&gt;LINKs series&lt;/i&gt;, 2019, pp.120-123</idno>
            <idno type="halRef">LINKs series, 2019, pp.120-123</idno>
            <availability status="restricted">
              <licence target="https://about.hal.science/hal-authorisation-v1/">HAL Authorization<ref corresp="#file-2532029-2405914"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UNIV-MONTPELLIER">Université de Montpellier</idno>
            <idno type="stamp" n="UM-2015-2021" corresp="UNIV-MONTPELLIER">Université de Montpellier (2015-2021)</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Is biological randomness a statistical physics concept?</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Ovidiu</forename>
                    <surname>Radulescu</surname>
                  </persName>
                  <email type="md5">5e6c2ac6e5af23359597262493d7302d</email>
                  <email type="domain">umontpellier.fr</email>
                  <idno type="idhal" notation="string">ovidiu-radulescu</idno>
                  <idno type="idhal" notation="numeric">740482</idno>
                  <idno type="halauthorid" notation="string">3670-740482</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-6453-5707</idno>
                  <idno type="IDREF">https://www.idref.fr/137807074</idno>
                  <affiliation ref="#struct-410122"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Adrian</forename>
                    <surname>Devenyi</surname>
                  </persName>
                  <idno type="halauthorid">1819035-0</idno>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">146548</idno>
                <idno type="issn">2592-6756</idno>
                <title level="j">LINKs series</title>
                <imprint>
                  <publisher>Louis-José Lestocart</publisher>
                  <biblScope unit="pp">120-123</biblScope>
                  <date type="datePub">2019-10-07</date>
                </imprint>
              </monogr>
              <ref type="publisher">http://links-series.com/wp-content/uploads/2019/11/LINKs-1-2.pdf</ref>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="halDomain" n="sdv.bibs">Life Sciences [q-bio]/Quantitative Methods [q-bio.QM]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>One indication of the relevance of stochastic laws in biology is the fact that genetically similar cells can behave in very different ways. This suggests an analogy with statistical physics, in which stochastic laws govern the behavior of large ensembles of particles. Biological randomness has important theoretical and practical consequences in medicine and may be responsible for the resistance of pathogens or cancer to drug treatment. Modeling biological randomness is now a major field in theoretical biology and has been approached with methods adapted from physics. Like in physics, biological systems are governed by hierarchical processes involving variables with different timescales. Contrary to most physical processes, biological systems can exhibit inversions in the relationship between timescale and hierarchical rank. As a consequence, microscopic fluctuations can be transmitted to and even amplified by the phenotype. Because of these peculiarities, new approaches are needed for the study of biological randomness.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="institution" xml:id="struct-410122" status="OLD">
          <idno type="ISNI">0000000120970141</idno>
          <idno type="ROR">https://ror.org/051escj72</idno>
          <orgName>Université de Montpellier</orgName>
          <orgName type="acronym">UM</orgName>
          <date type="end">2021-12-31</date>
          <desc>
            <address>
              <addrLine>163 rue Auguste Broussonnet - 34090 Montpellier</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.umontpellier.fr/</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>