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Article Dans Une Revue PLoS ONE Année : 2009

Involvement of Basal Ganglia Network in Motor Disabilities Induced by Typical Antipsychotics

Résumé

Clinical treatments with typical antipsychotic drugs (APDs) are accompanied by extrapyramidal motor side-effects (EPS) such as hypokinesia and catalepsy. As little is known about electrophysiological substrates of such motor disturbances, we investigated the effects of a typical APD, alpha-flupentixol, on the motor behavior and the neuronal activity of the whole basal ganglia nuclei in the rat.

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hal-02484681 , version 1 (19-02-2020)

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Jonathan Chetrit, Bérangère Ballion, Steeve Laquitaine, Pauline Belujon, Stéphanie Morin, et al.. Involvement of Basal Ganglia Network in Motor Disabilities Induced by Typical Antipsychotics. PLoS ONE, 2009, 4 (7), pp.e6208. ⟨10.1371/journal.pone.0006208⟩. ⟨hal-02484681⟩

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