NEURONAL CULTURE AT SINGLE CELL LEVEL FOR CREATION OF BIOLOGICAL NEURONAL NETWORK
Résumé
To understand the electrophysiological dynamics of neurons, the use of micro-electrode array (MEA) is common because it is non-invasive and it allows long-term monitoring. However, as the culture are randomly arranged on fixated electrodes, it is not capable of recording electrophysiology at single cell level. Here, we present a fully transparent neuronal culture device capable of monitoring cells growth or activity at single scale level. To trap cells singularly, dielectrophoresis is used on a ITO glass coated with fluoropolymer component called CYTOP® to manipulate cells.
Domaines
Sciences de l'ingénieur [physics]Origine | Fichiers produits par l'(les) auteur(s) |
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