Spatiotemporal Dynamics of Cortical Sensorimotor Integration in Behaving Mice - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Neuron Année : 2007

Spatiotemporal Dynamics of Cortical Sensorimotor Integration in Behaving Mice

Isabelle Ferezou
Florent Haiss
Luc J Gentet
  • Fonction : Auteur
  • PersonId : 1047633
Rachel Aronoff
Bruno Weber
  • Fonction : Auteur
Carl C. H. Petersen
  • Fonction : Auteur
  • PersonId : 940850

Résumé

Tactile information is actively acquired and processed in the brain through concerted interactions between movement and sensation. Somatosensory input is often the result of self-generated movement during the active touch of objects, and conversely, sensory information is used to refine motor control. There must therefore be important interactions between sensory and motor pathways, which we chose to investigate in the mouse whisker sensorimotor system. Voltage-sensitive dye was applied to the neocortex of mice to directly image the membrane potential dynamics of sensorimotor cortex with subcolumnar spatial resolution and millisecond temporal precision. Single brief whisker deflections evoked highly distributed depolarizing cortical sensory responses, which began in the primary somatosensory barrel cortex and subsequently excited the whisker motor cortex. The spread of sensory information to motor cortex was dynamically regulated by behavior and correlated with the generation of sensory-evoked whisker movement. Sensory processing in motor cortex may therefore contribute significantly to active tactile sensory perception.
Fichier principal
Vignette du fichier
Ferezou_Neuron_2007.pdf (3.18 Mo) Télécharger le fichier
Origine : Accord explicite pour ce dépôt

Dates et versions

hal-02439765 , version 1 (26-11-2020)

Identifiants

Citer

Isabelle Ferezou, Florent Haiss, Luc J Gentet, Rachel Aronoff, Bruno Weber, et al.. Spatiotemporal Dynamics of Cortical Sensorimotor Integration in Behaving Mice. Neuron, 2007, 56 (5), pp.907-923. ⟨10.1016/j.neuron.2007.10.007⟩. ⟨hal-02439765⟩
26 Consultations
80 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More