Comment on “Free-Radical Formation by the Peroxidase-Like Catalytic Activity of MFe 2 O 4 (M = Fe, Ni, and Mn) Nanoparticles”
Résumé
The peroxidase-like activity of magnetite and its connection with a neurodegenerative disease such as Alzheimer's disease has been recently questioned by our group, 1 despite claims by Gao et al. 2 Since reproducibility is the essential factor in experimental sciences, the article of Moreno Maldonado et al. on the peroxidase-like activity of magnetite attracted our attention. 3 As a matter of fact this new report is providing additional evidences on the absence of peroxidase activity of magnetite derivatives. The following comments are not a question of semantics, but are driven by the necessity to correctly describe the different possible origins of the oxidative stress involved in many neurodegenerative pathologies.
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