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Article Dans Une Revue Journal of Micromechanics and Microengineering Année : 2004

A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications

Résumé

We present a novel nanoelectrospray emitter tip based on the principle of a nib rather than a nozzle for nano-electrospray ionization-mass spectrometry (ESI-MS) applications. The fabrication of the micro-nibs relies on micromachining techniques using the epoxy-based negative photoresist SU-8. A double exposure photolithographic process has been employed to form a nib in a membrane-like structure. The nibs contained a capillary slot measuring 20 µm at the tip end. The nib sources were successfully tested on an ion trap mass spectrometer using standard peptide samples at low concentrations, down to 1 µM. High voltage (HV) supply was achieved using platinum wire inserted in a liquid reservoir. A Taylor cone was clearly seen protruding from the nib tip and was determined by the dimensions of the capillary slot.
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Dates et versions

hal-02347816 , version 1 (06-01-2021)

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S. Arscott, Séverine Le Gac, Christian Druon, Pierre Tabourier, Christian Rolando. A planar on-chip micro-nib interface for NanoESI–MS microfluidic applications. Journal of Micromechanics and Microengineering, 2004, 14 (2), pp.310-316. ⟨10.1088/0960-1317/14/2/021⟩. ⟨hal-02347816⟩
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