Arrays of high aspect ratio magnetic microstructures for large trapping throughput in lab-on-chip systems - Archive ouverte HAL Access content directly
Journal Articles Microfluidics and Nanofluidics Year : 2018

Arrays of high aspect ratio magnetic microstructures for large trapping throughput in lab-on-chip systems

Abstract

Here we report a novel technology to obtain arrays of highly efficient magnetic micro-traps that relies on simple fabrication process. Developed micro-traps consist in chains of iron particles diluted in polydimethylsiloxane (PDMS). We analyzed the microstructure of the composite membrane by X-ray tomography. It revealed the predominance of aligned chain-like agglomerates. Largest traps, with diameter ranging from 4 to 11 µm, are found to be the most efficient. The trap arrays were characterized by a density of 1300 magnetic micro-traps/mm2, an average nearest neighbor distance of 21 µm. Implemented in a microfluidic channel operating at a relatively high flow rate of 0.97 µL/s—a flow velocity of 8.3 mm/s—we measured a trapping efficiency of more than 99.7%, with a throughput of up to 7100 trapped beads/min. These performances are competitive with other approaches like hydrodynamic trapping. The strengths of this technology are its simple fabrication and easy handling.
Fichier principal
Vignette du fichier
Mekkaoui_2018.pdf (1.27 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-02326961 , version 1 (22-10-2019)

Identifiers

Cite

Samir Mekkaoui, Damien Le Roy, Marie-Charlotte Audry, Joël Lachambre, Véronique Dupuis, et al.. Arrays of high aspect ratio magnetic microstructures for large trapping throughput in lab-on-chip systems. Microfluidics and Nanofluidics, 2018, 22 (10), pp.119. ⟨10.1007/s10404-018-2141-6⟩. ⟨hal-02326961⟩
113 View
108 Download

Altmetric

Share

Gmail Facebook X LinkedIn More