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Article Dans Une Revue Anaesthesia Critical Care & Pain Medicine Année : 2019

Update in Antibiotic Therapy in Intensive Care Unit Report from the 2019 Nimes International Symposium

Adrien Bouglé
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Didier Payen
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Résumé

The 2019 Nîmes International Symposium in Antibiotic Therapy Optimisation aimed at determining the best approaches of a number of the antibiotic management strategies for critically ill patients. Experts reviewed the latest literature relating to requirements for an optimal antibiotic stewardship program, risks of sub-therapeutic dosing of antibiotics in critically ill patients, persisting issues about efficiency of combination therapy and the value of de-escalation, new perspectives of pharmacokinetics, drug toxicities including collateral damages-associated with antibiotics, the place of nebulisation of antibiotics, management of patients receiving extracorporeal therapies and the place of new antibiotics. In this paper, each of these issues is discussed with key messages presented after a brief review of evidence.
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Dates et versions

hal-02316049 , version 1 (10-06-2020)

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Marc Leone, Jason Roberts, Matteo Bassetti, Adrien Bouglé, Jean-Philippe Lavigne, et al.. Update in Antibiotic Therapy in Intensive Care Unit Report from the 2019 Nimes International Symposium. Anaesthesia Critical Care & Pain Medicine, 2019, 38 (6), pp.647-656. ⟨10.1016/j.accpm.2019.09.009⟩. ⟨hal-02316049⟩
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