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Article Dans Une Revue Trends in Parasitology Année : 2005

Towards a new conceptual approach to ‘parasitoproteomics’

Résumé

Many parasitologists are betting heavily on proteomic studies to explain biochemical host-parasite interactions and, thus, to contribute to disease control. However, many 'parasitoproteomic' studies are performed with powerful techniques but without a conceptual approach to determine whether the host genomic responses during a parasite infection represent a nonspecific response that might be induced by any parasite or any other stress. In this article, a new conceptual approach, based on evolutionary concepts of immune responses of a host to a parasite, is suggested for parasitologists; to study the host proteome reaction after parasite invasion. Also, this new conceptual approach can be used to study other host-parasite interactions such as behavioral manipulation.
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hal-02308020 , version 1 (08-04-2024)

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David Biron, Hercules Moura, Laurent Marché, Austin Hughes, Frédéric Thomas. Towards a new conceptual approach to ‘parasitoproteomics’. Trends in Parasitology, 2005, 21 (4), pp.162-168. ⟨10.1016/j.pt.2005.02.009⟩. ⟨hal-02308020⟩
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