High resolution X-ray diffraction, ab initio calculations and thermodynamic measurements to go insight the polymorphism of drugs. Application to paracetamol and piracetam
Résumé
Studying polymorphism of pharmaceutical compounds is a growing field of activity. This is due to the economic pressure of the pharmaceutical industry and the more important awareness of the polymorphism consequences on the medicament properties, in particular chemical and physical stability. We have developed a fundamental approach to study polymorphism, which combines high-resolution X-ray diffraction, thermodynamic experiments and ab-initio calculations
| Origine | Fichiers produits par l'(les) auteur(s) |
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