Identification of essential outstanding questions for an adequate European laboratory response to Ebolavirus Zaire West Africa 2014
Chantal Reusken
(1)
,
Matthias Niedrig
(2)
,
Suzan Pas
(1)
,
Pedro Anda
(3)
,
Sylvain Baize
(4)
,
Remi Charrel
(5)
,
Antonino Di Caro
(6)
,
Christian Drosten
(7)
,
Maria Dolores Fernandez-Garcia
(3)
,
Leticia Franco
(3)
,
Stephan Günther
(8)
,
Isabelle Leparc-Goffart
(9)
,
Byron E E Martina
(10, 11)
,
Delphine Pannetier
(4)
,
Anna Papa
(12)
,
Maria Paz Sanchez-Seco
(3)
,
Olli Vapalahti
(13, 14)
,
Marion P Koopmans
(1, 15)
1
Department of Viroscience [Rotterdam, The Netherlands]
2 RKI - Robert Koch Institute [Berlin]
3 Institute of Health Carlos III
4 UBIVE - Biologie des Infections Virales Émergentes - Biology of Emerging Viral Infections [CIRI]
5 EPV - Emergence des Pathologies Virales
6 Laboratory of microbiology and biorepository
7 Institut für Virologie / Institute of Virology [Bonn, Germany]
8 Department of Virology
9 IRBA - Institut de Recherche Biomédicale des Armées [Antenne Marseille]
10 BNITM - Bernhard Nocht Institute for Tropical Medicine - Bernhard-Nocht-Institut für Tropenmedizin [Hamburg, Germany]
11 DZIF - German Center for Infection Research - partner site Hannover-Braunschweig
12 Aristotle University of Thessaloniki
13 Department of Virology [Helsinki]
14 Department of Veterinary Biosciences, Faculty of Veterinary Medicine
15 Centre for Infectious Disease Control Netherlands
2 RKI - Robert Koch Institute [Berlin]
3 Institute of Health Carlos III
4 UBIVE - Biologie des Infections Virales Émergentes - Biology of Emerging Viral Infections [CIRI]
5 EPV - Emergence des Pathologies Virales
6 Laboratory of microbiology and biorepository
7 Institut für Virologie / Institute of Virology [Bonn, Germany]
8 Department of Virology
9 IRBA - Institut de Recherche Biomédicale des Armées [Antenne Marseille]
10 BNITM - Bernhard Nocht Institute for Tropical Medicine - Bernhard-Nocht-Institut für Tropenmedizin [Hamburg, Germany]
11 DZIF - German Center for Infection Research - partner site Hannover-Braunschweig
12 Aristotle University of Thessaloniki
13 Department of Virology [Helsinki]
14 Department of Veterinary Biosciences, Faculty of Veterinary Medicine
15 Centre for Infectious Disease Control Netherlands
Sylvain Baize
- Fonction : Auteur
- PersonId : 746348
- IdHAL : sylvain-baize
- ORCID : 0000-0002-3234-7477
- IdRef : 129432164
Remi Charrel
- Fonction : Auteur
- PersonId : 765912
- ORCID : 0000-0002-7675-8251
- IdRef : 129311200
Christian Drosten
- Fonction : Auteur
- PersonId : 925428
Olli Vapalahti
- Fonction : Auteur
- PersonId : 881527
Marion P Koopmans
- Fonction : Auteur
- PersonId : 1023428
Résumé
On August 8 2014, the World Health Organization (WHO) declared the outbreak of Ebola Virus Disease (EVD) evolving in West Africa since December 2013, a Public Health Emergency of International Concern (PHEIC). It is expected that the outbreak of Ebolavirus Disease (EVD) in West Africa will lead to increased testing of individuals in Europe for EVD. The severity of the situation in West Africa warranted a critical appraisal of the laboratory preparedness and response for EVD, with a focus on information needs for laboratories involved in diagnostics of rare viral diseases associated with the European Network for the Diagnostics of "Imported" Viral Diseases", ENIVD. Essential knowledge and knowledge gaps for an adequate laboratory response focusing on virus properties, infection kinetics, tests specifics and field performances were identified. An inventory of the laboratory capacity for EVD diagnostics among ENIVD laboratories was made.