Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014
Jens Kuhn
(1)
,
Kristian Andersen
(2)
,
Sylvain Baize
(3)
,
Yīmíng Bào
(4)
,
Sina Bavari
(5)
,
Nicolas Berthet
(6)
,
Olga Blinkova
(4)
,
J Rodney Brister
(4)
,
Anna Clawson
(1)
,
Joseph Fair
(7)
,
Martin Gabriel
(8, 9)
,
Robert Garry
(10)
,
Stephen Gire
(11)
,
Augustine Goba
(12)
,
Jean-Paul Gonzalez
(13)
,
Stephan Günther
(8, 9)
,
Christian Happi
(14)
,
Peter Jahrling
(1)
,
Jimmy Kapetshi
(15)
,
Gary Kobinger
(16)
,
Jeffrey Kugelman
(5)
,
Eric M. Leroy
(6)
,
Gael Darren Maganga
(6)
,
Placide Mbala
(15)
,
Lina Moses
(10)
,
Jean-Jacques Muyembe-Tamfum
(15)
,
Magassouba N'Faly
(17, 18, 19)
,
Stuart Nichol
(20)
,
Sunday Omilabu
(21)
,
Gustavo Palacios
(5)
,
Daniel Park
(22)
,
Janusz Paweska
(23)
,
Sheli Radoshitzky
(5)
,
Cynthia Rossi
(5)
,
Pardis Sabeti
(2)
,
John Schieffelin
(10)
,
Randal Schoepp
(5)
,
Rachel Sealfon
(24)
,
Robert Swanepoel
(25)
,
Jonathan Towner
(20)
,
Jiro Wada
(1)
,
Nadia Wauquier
(13)
,
Nathan Yozwiak
(2, 22)
,
Pierre Formenty
(26)
1
NIAID-NIH -
National Institute of Allergy and Infectious Diseases [Bethesda]
2 FAS Center for Systems Biology
3 UBIVE - Biologie des Infections Virales Émergentes - Biology of Emerging Viral Infections [CIRI]
4 NCBI - National Center for Biotechnology Information
5 USAMRIID - U.S. Army Medical Research Institute of Infectious Diseases
6 CIRMF - Centre International de Recherches Médicales de Franceville
7 Fondation Mérieux
8 BNITM - Bernhard Nocht Institute for Tropical Medicine - Bernhard-Nocht-Institut für Tropenmedizin [Hamburg, Germany]
9 DZIF - German Center for Infection Research, Partnersite Munich
10 Tulane University
11 Harvard FAS Center for Systems Biologyy
12 Kenema Government Hospital
13 Metabiota Inc. [San Francisco]
14 Redeemer's University [Lagos, Nigeria]
15 INRB - Institut National de Recherche Biomédicale [Kinshasa]
16 Special Pathogens Programme, National Microbiology Laboratory
17 Université Gamal Abdel Nasser de Conakry
18 Laboratoire des Fièvres Hémorragiques en Guinée
19 Donka National Hospital
20 CDC - Centers for Disease Control and Prevention [Atlanta]
21 Department of Medical Microbiology and Parasitology, College of Medicine
22 Broad Institute [Cambridge]
23 NICD - National Institute for Communicable Diseases [Johannesburg]
24 CSAIL - Computer Science and Artificial Intelligence Laboratory [Cambridge]
25 University of Pretoria [South Africa]
26 OMS / WHO - Organisation Mondiale de la Santé / World Health Organization Office [Genève, Suisse]
2 FAS Center for Systems Biology
3 UBIVE - Biologie des Infections Virales Émergentes - Biology of Emerging Viral Infections [CIRI]
4 NCBI - National Center for Biotechnology Information
5 USAMRIID - U.S. Army Medical Research Institute of Infectious Diseases
6 CIRMF - Centre International de Recherches Médicales de Franceville
7 Fondation Mérieux
8 BNITM - Bernhard Nocht Institute for Tropical Medicine - Bernhard-Nocht-Institut für Tropenmedizin [Hamburg, Germany]
9 DZIF - German Center for Infection Research, Partnersite Munich
10 Tulane University
11 Harvard FAS Center for Systems Biologyy
12 Kenema Government Hospital
13 Metabiota Inc. [San Francisco]
14 Redeemer's University [Lagos, Nigeria]
15 INRB - Institut National de Recherche Biomédicale [Kinshasa]
16 Special Pathogens Programme, National Microbiology Laboratory
17 Université Gamal Abdel Nasser de Conakry
18 Laboratoire des Fièvres Hémorragiques en Guinée
19 Donka National Hospital
20 CDC - Centers for Disease Control and Prevention [Atlanta]
21 Department of Medical Microbiology and Parasitology, College of Medicine
22 Broad Institute [Cambridge]
23 NICD - National Institute for Communicable Diseases [Johannesburg]
24 CSAIL - Computer Science and Artificial Intelligence Laboratory [Cambridge]
25 University of Pretoria [South Africa]
26 OMS / WHO - Organisation Mondiale de la Santé / World Health Organization Office [Genève, Suisse]
Jens Kuhn
- Fonction : Auteur
- PersonId : 775670
- ORCID : 0000-0003-3258-930X
Sylvain Baize
- Fonction : Auteur
- PersonId : 746348
- IdHAL : sylvain-baize
- ORCID : 0000-0002-3234-7477
- IdRef : 129432164
Nicolas Berthet
- Fonction : Auteur
- PersonId : 751043
- IdHAL : nicolas-berthet
J Rodney Brister
- Fonction : Auteur
- PersonId : 771120
- ORCID : 0000-0002-2249-975X
Gustavo Palacios
- Fonction : Auteur
- PersonId : 771122
- ORCID : 0000-0001-5062-1938
Résumé
In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological and evolutionary analyses confirmed that all cases of both outbreaks are connected to a single introduction each of EBOV into human populations and that both outbreaks are not directly connected. Coding-complete genomic sequence analyses of isolates revealed that the two outbreaks were caused by two novel EBOV variants, and initial clinical observations suggest that neither of them should be considered strains. Here we present consensus decisions on naming for both variants (West Africa: "Makona", Middle Africa: "Lomela") and provide database-compatible full, shortened, and abbreviated names that are in line with recently established filovirus sub-species nomenclatures.