<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-02272318</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-19T06:57:34+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Can secondary contact following range expansion be distinguished from barriers to gene flow?</title>
            <author role="aut">
              <persName>
                <forename type="first">Johanna</forename>
                <surname>Bertl</surname>
              </persName>
              <idno type="halauthorid">1640832-0</idno>
              <affiliation ref="#struct-19908"/>
              <affiliation ref="#struct-549779"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Harald</forename>
                <surname>Ringbauer</surname>
              </persName>
              <idno type="halauthorid">1640833-0</idno>
              <affiliation ref="#struct-258666"/>
              <affiliation ref="#struct-115321"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Michael G.B.</forename>
                <surname>Blum</surname>
              </persName>
              <idno type="halauthorid">1640834-0</idno>
              <affiliation ref="#struct-1042063"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Catherine</forename>
                <surname>ZOPPIS</surname>
              </persName>
              <email type="md5">6dd921a6b2d3ffcc35d48c9c0d521def</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
            </editor>
            <funder ref="#projanr-42467"/>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2019-08-27 16:22:24</date>
              <date type="whenModified">2025-09-27 18:43:42</date>
              <date type="whenReleased">2019-08-27 16:22:24</date>
              <date type="whenProduced">2018</date>
              <ref type="externalLink" target="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171497"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="469462">
                <persName>
                  <forename>Catherine</forename>
                  <surname>ZOPPIS</surname>
                </persName>
                <email type="md5">6dd921a6b2d3ffcc35d48c9c0d521def</email>
                <email type="domain">univ-grenoble-alpes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-02272318</idno>
            <idno type="halUri">https://hal.science/hal-02272318</idno>
            <idno type="halBibtex">bertl:hal-02272318</idno>
            <idno type="halRefHtml">&lt;i&gt;PeerJ&lt;/i&gt;, 2018, 6, pp.e5325. &lt;a target="_blank" href="https://dx.doi.org/10.7717/peerj.5325"&gt;&amp;#x27E8;10.7717/peerj.5325&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">PeerJ, 2018, 6, pp.e5325. &amp;#x27E8;10.7717/peerj.5325&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="TIMC-IMAG-BCM" corresp="TIMC-IMAG">BCM : Biologie Computationnelle et Mathématique</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="UGA-COMUE">Université Grenoble Alpes [2016-2019]</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Can secondary contact following range expansion be distinguished from barriers to gene flow?</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Johanna</forename>
                    <surname>Bertl</surname>
                  </persName>
                  <idno type="halauthorid">1640832-0</idno>
                  <affiliation ref="#struct-19908"/>
                  <affiliation ref="#struct-549779"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Harald</forename>
                    <surname>Ringbauer</surname>
                  </persName>
                  <idno type="halauthorid">1640833-0</idno>
                  <affiliation ref="#struct-258666"/>
                  <affiliation ref="#struct-115321"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Michael G.B.</forename>
                    <surname>Blum</surname>
                  </persName>
                  <idno type="halauthorid">1640834-0</idno>
                  <affiliation ref="#struct-1042063"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">104712</idno>
                <idno type="issn">2167-8359</idno>
                <title level="j">PeerJ</title>
                <imprint>
                  <publisher>PeerJ</publisher>
                  <biblScope unit="volume">6</biblScope>
                  <biblScope unit="pp">e5325</biblScope>
                  <date type="datePub">2018</date>
                </imprint>
              </monogr>
              <idno type="doi">10.7717/peerj.5325</idno>
              <idno type="pubmedcentral">PMC6171497</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Secondary contact</term>
                <term xml:lang="en">Quaternary glaciation</term>
                <term xml:lang="en">Landscape genetics</term>
                <term xml:lang="en">Isolation-by-distance</term>
                <term xml:lang="en">Isolation with migration models</term>
                <term xml:lang="en">Hybrid zone</term>
                <term xml:lang="en">Barrier of gene-flow</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Secondary contact is the reestablishment of gene flow between sister populations that have diverged. For instance, at the end of the Quaternary glaciations in Europe, secondary contact occurred during the northward expansion of the populations which had found refugia in the southern peninsulas. With the advent of multi-locus markers, secondary contact can be investigated using various molecular signatures including gradients of allele frequency, admixture clines, and local increase of genetic differentiation. We use coalescent simulations to investigate if molecular data provide enough information to distinguish between secondary contact following range expansion and an alternative evolutionary scenario consisting of a barrier to gene flow in an isolation-by-distance model. We find that an excess of linkage disequilibrium and of genetic diversity at the suture zone is a unique signature of secondary contact. We also find that the directionality index ψ, which was proposed to study range expansion, is informative to distinguish between the two hypotheses. However, although evidence for secondary contact is usually conveyed by statistics related to admixture coefficients, we find that they can be confounded by isolation-by-distance. We recommend to account for the spatial repartition of individuals when investigating secondary contact in order to better reflect the complex spatio-temporal evolution of populations and species.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="institution" xml:id="struct-19908" status="VALID">
          <idno type="IdRef">026461307</idno>
          <idno type="ROR">https://ror.org/01aj84f44</idno>
          <orgName>Aarhus University [Aarhus]</orgName>
          <desc>
            <address>
              <addrLine>Nordre Ringgade 1 DK-8000 Aarhus C</addrLine>
              <country key="DK"/>
            </address>
            <ref type="url">http://www.au.dk/en/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-549779" status="INCOMING">
          <orgName>Vetmeduni Vienna</orgName>
          <desc>
            <address>
              <country key="AU"/>
            </address>
          </desc>
        </org>
        <org type="institution" xml:id="struct-258666" status="VALID">
          <orgName>The University of Chicago Medicine [Chicago]</orgName>
          <desc>
            <address>
              <addrLine>5841 S. Maryland Avenue Chicago, IL 60637</addrLine>
              <country key="US"/>
            </address>
            <ref type="url">http://www.uchospitals.edu</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-115321" status="VALID">
          <orgName>Institute of Science and Technology [Klosterneuburg, Austria]</orgName>
          <orgName type="acronym">IST Austria</orgName>
          <desc>
            <address>
              <addrLine>IST Austria Am Campus 1 3400 Klosterneuburg Austria</addrLine>
              <country key="AT"/>
            </address>
            <ref type="url">http://www.ist.ac.at/</ref>
          </desc>
        </org>
        <org type="researchteam" xml:id="struct-1042063" status="OLD">
          <orgName>Biologie Computationnelle et Mathématique</orgName>
          <orgName type="acronym">TIMC-IMAG-BCM</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-1042061" type="direct"/>
            <relation active="#struct-89889" type="indirect"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
            <relation active="#struct-445543" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1042061" status="OLD">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525</orgName>
          <orgName type="acronym">TIMC-IMAG</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www-timc.imag.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-89889" type="direct"/>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
            <relation active="#struct-445543" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-89889" status="OLD">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2007-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-445543" status="OLD">
          <idno type="IdRef">188399275</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes [2016-2019]</orgName>
          <orgName type="acronym">UGA [2016-2019]</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2019-12-31</date>
          <desc>
            <address>
              <addrLine>38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-42467" status="VALID">
          <idno type="anr">ANR-15-IDEX-0002</idno>
          <orgName>UGA</orgName>
          <desc>IDEX UGA</desc>
          <date type="start">2015</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>