Article Dans Une Revue Nucleic Acids Research Année : 1984

Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues

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We have isolated and identified cDNA clones containing part of the coding sequence for rat glyceraldehyde-3-phosphate-dehydrogenase (GAPDH, E.C. 1.2.1.12). By using one of these clones as a probe, we have shown that: i) the abundance of GAPDH mRNA is different in various tissues of the adult rat and in good correlation with the abundance of the enzyme; ii) the transcription rates are quite similar in all tissues tested. We therefore conclude that the tissue-specific differential GAPDH gene expression is regulated by adjusting the abundance of its mRNA at the post-transcriptional level.

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hal-02267593 , version 1 (26-06-2020)

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Marc Piechaczyk, Jean-Marie Blanchard, Louise Marty, Christian Dani, Franck Panabieres, et al.. Post-transcriptional regulation of glyceraldehyde-3-phosphate-dehydrogenase gene expression in rat tissues. Nucleic Acids Research, 1984, 12 (18), pp.6951-6963. ⟨10.1093/nar/12.18.6951⟩. ⟨hal-02267593⟩
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