E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation
Mots clés
Post-Translational Protein Structure
Tertiary Protein Transport/radiation effects Proto-Oncogene Proteins c-mdm2/metabolism Repressor Proteins/chemistry/*metabolism Sequence Homology
Genetic/radiation effects Tumor Cells
Cultured Tumor Suppressor Protein p53/*metabolism Ubiquitin-Protein Ligases/*metabolism Ultraviolet Rays p300-CBP Transcription Factors
Cell Nucleus/radiation effects Amino Acid Sequence Apoptosis/radiation effects Cell Cycle Proteins/metabolism Chromatin/metabolism Histone Acetyltransferases/metabolism Humans Lysine/metabolism Molecular Sequence Data *Protein Processing
Amino Acid Thermodynamics Transcription Factors/metabolism Transcription
Acetylation/radiation effects Active Transport