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Article Dans Une Revue Scientific Reports Année : 2019

A new computational approach to estimate whole-brain effective connectivity from functional and structural MRI, applied to language development

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Recently introduced effective connectivity methods allow for the in-vivo investigation of large-scale functional interactions between brain regions. However, dynamic causal modeling, the most widely used technique to date, typically captures only a few predefined regions of interest. In this study, we present an alternative computational approach to infer effective connectivity within the entire connectome and show its performance on a developmental cohort with emerging language capacities. The novel approach provides new opportunities to quantify effective connectivity changes in the human brain.
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hal-02190758 , version 1 (08-09-2023)

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Gerald Hahn, Michael Skeide, Dante Mantini, Marco Ganzetti, Alain Destexhe, et al.. A new computational approach to estimate whole-brain effective connectivity from functional and structural MRI, applied to language development. Scientific Reports, 2019, 9 (1), pp.8479. ⟨10.1038/s41598-019-44909-6⟩. ⟨hal-02190758⟩
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