Lytic xylan oxidases from wood-decay fungi unlock biomass degradation - Archive ouverte HAL Access content directly
Journal Articles Nature Chemical Biology Year : 2018

Lytic xylan oxidases from wood-decay fungi unlock biomass degradation

Marie Couturier
Simon Ladeveze
Sacha Grisel
  • Function : Author
  • PersonId : 1203965
Nicolas Lenfant
Jean-Guy Berrin
  • Function : Author
  • PersonId : 1203881

Abstract

Wood biomass is the most abundant feedstock envisioned for the development of modern biorefineries. However, the cost-effective conversion of this form of biomass into commodity products is limited by its resistance to enzymatic degradation. Here we describe a new family of fungal lytic polysaccharide monooxygenases (LPMOs) prevalent among white-rot and brown-rot basidiomycetes that is active on xylans—a recalcitrant polysaccharide abundant in wood biomass. Two AA14 LPMO members from the white-rot fungus Pycnoporus coccineus substantially increase the efficiency of wood saccharification through oxidative cleavage of highly refractory xylan-coated cellulose fibers. The discovery of this unique enzyme activity advances our knowledge on the degradation of woody biomass in nature and offers an innovative solution for improving enzyme cocktails for biorefinery applications.
Fichier principal
Vignette du fichier
2018_Couturier_final.pdf (240.6 Ko) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-02188478 , version 1 (19-07-2019)

Identifiers

Cite

Marie Couturier, Simon Ladeveze, Gerlind Sulzenbacher, Luisa Ciano, Mathieu Fanuel, et al.. Lytic xylan oxidases from wood-decay fungi unlock biomass degradation. Nature Chemical Biology, 2018, 14 (3), pp.306-310. ⟨10.1038/nchembio.2558⟩. ⟨hal-02188478⟩
353 View
403 Download

Altmetric

Share

Gmail Facebook X LinkedIn More