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              <p>The purpose of this study was to investigate bone microarchitecture of cadaveric proximal femurs using ultra-high field (UHF) 7-Tesla magnetic resonance imaging (MRI) and to compare the corresponding metrics with failure load assessed during mechanical compression test and areal bone mineral density (ABDM) measured using dual-energy X-ray absorptiometry.Materials and methods: ABDM of ten proximal femurs from five cadavers (5 women; mean age= 86.2 ± 3.8 (SD) years; range : 82.5-90 years) were investigated using dual-energy X-ray absorptiometry and the bone volume fraction, trabecular thickness, trabecular spacing, fractal dimension, Euler characteristics, Connectivity density and degree of anisotropy of each femur was quantified using UHF MRI. The whole set of specimens underwent mechanical compression tests to failure. Associations were searched using correlation tests and multiple regression analysis.</p>
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            </address>
            <ref type="url">http://crmbm.univ-amu.fr/?lang=en</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300093" type="direct"/>
            <relation active="#struct-480402" type="direct"/>
            <relation name="UMR7339" active="#struct-198056" type="indirect"/>
            <relation name="UMR7339" active="#struct-300073" type="indirect"/>
            <relation name="UMR7339" active="#struct-441569" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-477182" status="VALID">
          <orgName>Siemens Healthcare</orgName>
          <desc>
            <address>
              <addrLine>Los Angeles, California, USA</addrLine>
              <country key="US"/>
            </address>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-460887" status="VALID">
          <orgName>Service de Rhumatologie [CHU Sainte Marguerite]</orgName>
          <desc>
            <address>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-300889" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-198056" status="VALID">
          <idno type="IdRef">15863621X</idno>
          <idno type="ISNI">0000 0001 2176 4817</idno>
          <idno type="ROR">https://ror.org/035xkbk20</idno>
          <orgName>Aix Marseille Université</orgName>
          <orgName type="acronym">AMU</orgName>
          <date type="start">2012-01-01</date>
          <desc>
            <address>
              <addrLine>Aix-Marseille UniversitéJardins du Pharo58 Boulevard Charles Livon13284 Marseille cedex 7</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-amu.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-300073" status="VALID">
          <idno type="ROR">https://ror.org/002cp4060</idno>
          <orgName>Assistance Publique - Hôpitaux de Marseille</orgName>
          <orgName type="acronym">APHM</orgName>
          <desc>
            <address>
              <addrLine>Direction générale AP-HM80, rue Brochier13 354 Marseille Cedex 5</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://fr.ap-hm.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-300093" status="VALID">
          <idno type="ISNI">0000 0001 0404 1115 </idno>
          <idno type="ROR">https://ror.org/05jrr4320</idno>
          <orgName>Hôpital de la Timone [CHU - APHM]</orgName>
          <orgName type="acronym">TIMONE</orgName>
          <date type="start">1974-01-01</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">http://fr.ap-hm.fr/nos-hopitaux/hopital-de-la-timone</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>