Highlighting the Potency of Biosurfactants Produced by Pseudomonas Strains as Anti- Legionella Agents - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue BioMed Research International Année : 2018

Highlighting the Potency of Biosurfactants Produced by Pseudomonas Strains as Anti- Legionella Agents

Résumé

Legionella pneumophila, the causative agent of Legionnaires' disease, is a waterborne bacterium mainly found in man-made water systems in close association with free-living amoebae and multispecies biofilms. Pseudomonas strains, originating from various environments including freshwater systems or isolated from hospitalized patients, were tested for their antagonistic activity towards L. pneumophila. A high amount of tested strains was thus found to be active. This antibacterial activity was correlated to the presence of tensioactive agents in culture supernatants. As Pseudomonas strains were known to produce biosurfactants, these compounds were specifically extracted and purified from active strains and further characterized using reverse-phase HPLC and mass spectrometry methods. Finally, all biosurfactants tested (lipopeptides and rhamnolipids) were found active and this activity was shown to be higher towards Legionella strains compared to various other bacteria. Therefore, described biosurfactants are potent anti-Legionella agents that could be used in the water treatment industry although tests are needed to evaluate how effective they would be under field conditions.
Fichier principal
Vignette du fichier
Loiseau 2018.pdf (1.46 Mo) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02176315 , version 1 (08-07-2019)

Licence

Paternité

Identifiants

Citer

Clémence Loiseau, Emilie Portier, Marie-Hélène Corre, Margot Schlusselhuber, Segolene Depayras, et al.. Highlighting the Potency of Biosurfactants Produced by Pseudomonas Strains as Anti- Legionella Agents. BioMed Research International , 2018, 2018, pp.1-15. ⟨10.1155/2018/8194368⟩. ⟨hal-02176315⟩
42 Consultations
60 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More