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Journal Articles Nature Genetics Year : 2019

Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen Huyghe (1) , Stephanie Bien , Tabitha Harrison , Hyun Min Kang , Sai Chen , Stephanie Schmit , David Conti , Conghui Qu , Jihyoun Jeon , Christopher Edlund , Peyton Greenside , Michael Wainberg , Fredrick R Schumacher (2) , Joshua Smith , David Levine , Sarah Nelson , Nasa Sinnott-Armstrong , Demetrius Albanes (3) , M. Henar Alonso , Kristin Anderson , Coral Arnau-Collell , Volker Arndt (4) , Christina Bamia (5) , Barbara Banbury , John Baron , Sonja I Berndt (6) , Stéphane Bézieau (7) , D. Timothy Bishop , Juergen Boehm , Heiner Boeing (8) , Hermann Brenner (9) , Stefanie Brezina , Stephan Buch , Daniel Buch , Andrea Burnett-Hartman , Katja Butterbach (10) , Bette Caan , Peter J Campbell (11) , Christopher Carlson , Sergi Castellví-Bel , Andrew Chan , Jenny Chan (12) , Stephen Chan , María-Dolores Chirlaque (13) , Sang Hee Cho , Charles Connolly , Amanda Cross , Katarina Cuk , Keith Curtis (14) , Albert de La Chapelle (15) , Kimberly Doheny , David Duggan , Douglas Easton (16) , Sjoerd Elias , Faye Elliott (17) , Dallas R English (18) , Edith Feskens (19) , Jane Figueiredo , Rocky Fischer , Liesel M. Fitzgerald (20) , David Forman (21) , Manish Gala , Steven Gallinger (22) , W. James Gauderman , Graham G Giles (23) , Elizabeth Gillanders , Jian Gong , Phyllis Goodman , William Grady , John Grove , Andrea Gsur , Marc Gunter (24) , Robert Haile , Jochen Hampe (25) , Heather Hampe , Sophia Harlid , Richard Hayes (26) , Philipp Hofer , Michael Hoffmeister (27) , John Hopper (28) , Wan-Ling Hsu , Wen-Yi Huang , Thomas J. Hudson (29) , David R. Hunter (30) , Gemma Ibañez-Sanz , Gregory Idos , Roxann Ingersoll , Rebecca Jackson , Eric Jacobs , Mark Jenkins , Amit J Joshi (31) , Corinne Joshu , Temitope Keku , Timothy Key (32) , Hyeong Rok Kim , Emiko Kobayashi , Laurence Kolonel , Charles Kooperberg , Tilman Kühn (33) , Sébastien Küry (7) , Sun-Seog Kweon , Susanna Larsson , Cecelia Laurie , Marc Le Marchand , Suzanne M. Leal (34) , Soo Chin Lee (35) , Flavio Lejbkowicz (36) , Mathieu Lemire (37) , Christopher Li , Li Li (38) , Tin Louie , Satu Männistö (39) , Mark Markowitz , Vicente Martín (40) , Giovanna Masala (41) , Caroline Mcneil , Marilena Melas , Roger L Milne (18) , Lorena Moreno , Neil Murphy , Robin Myte , Alessio Naccarati , Polly Newcomb , Kenneth Offit (42) , Shuji Ogino (43) , N. Charlotte Onland-Moret (44) , Barbara Pardini , Patrick Parfrey , Rachel Pearlman , Vittorio Perduca (45) , Paul Pharoah (46) , Mila Pinchev , Elizabeth Platz , Ross Prentice , Elizabeth Pugh , Leon Raskin , Gad Rennert (36) , Hedy Rennert , Elio Riboli (47) , Miguel Rodríguez-Barranco , Jane Romm , Lori Sakoda , Clemens Schafmayer (48) , Robert Schoen , Daniel Seminara , Mitul Shah , Tameka Shelford , Min-Ho Shin , Katerina Shulman , Sabina Sieri (49) , Martha Slattery , Melissa Southey (50) , Zsofia Stadler , Christa Stegmaier , Yu-Ru Su , Catherine M Tangen (51) , Stephen N. Thibodeau (52) , Thomas Thomas , Thomas Su , Amanda Toland (53) , Antonia Trichopoulou (54) , Cornelia Ulrich , David van den Berg , Franzel van Duijnhoven , Bethany van Guelpen (55) , Henk van Kranen , Joseph Vijai (56) , Kala Visvanathan , Pavel Vodicka (57) , Ludmila Vodickova , Veronika Vymetalkova , Korbinian Weigl , Stephanie Weinstein , Emily White , Aung Ko Win , C. Roland Wolf (58) , Alicja Wolk (59) , Michael Woods , Anna Wu , Syed Zaidi , Brent Zanke , Qing Zhang (60) , Wei Zheng (61) , Peter Scacheri , John Potter , Michael Bassik , Anshul Kundaje (62) , Graham Casey (63) , Victor Moreno (64) , Goncalo Abecasis (65) , Deborah A Nickerson (66) , Stephen B. Gruber (67) , Li Hsu , Peter Peters (68)
1 Department of Medical Genetics
2 Case Western Reserve University [Cleveland]
3 National Cancer Institute, NIH
4 Division of Clinical Epidemiology and Aging Research
5 WHO Collaborating Center for Food and Nutrition Policies, Department of Hygiene
6 NCI-NIH - National Cancer Institute [Bethesda]
7 Service de Génétique
8 Department of Epidemiology
9 Division of Clinical Epidemiology and Aging Research
10 Division of Cancer Epidemiology
11 Cancer Genome Project
12 Division of Signaling Biology
13 CIBERESP - Consorcio de Investigación Biomédica en Red especializado en Epidemiología y Salud Pública
14 NIST - National Institute of Standards and Technology [Gaithersburg]
15 OSU - Ohio State University [Columbus]
16 Centre for Cancer Genetic Epidemiology
17 Section of Epidemiology and Biostatistics
18 Cancer Epidemiology Centre
19 Division of Human Nutrition
20 Division of Public Health Sciences
21 Northern and Yorkshire Cancer Registry and Information Service
22 Familial Gastrointestinal Cancer Registry
23 University of Melbourne
24 Nutrition and Metabolism Section
25 Department of Internal Medicine I
26 LSHTM - London School of Hygiene and Tropical Medicine
27 Fraunhofer IPA - Fraunhofer Institute for Manufacturing Engineering and Automation
28 Centre for Molecular , Environmental, Genetic and Analytic (MEGA) Epidemiology
29 Department of Mathematics, University of Warwick
30 Department of Statistics, Penn State University
31 Tata Memorial Centre
32 Cancer Epidemiology Unit
33 Thermo Fisher Scientific
34 Department of Molecular and Human Genetics
35 National University Health System
36 Department of Community Medicine and Epidemiology
37 OICR - Ontario Institute for Cancer Research [Canada]
38 G2ELab - Laboratoire de Génie Electrique de Grenoble
39 Chronic Disease Epidemiology and Prevention Unit
40 Dell-EMC
41 ISPO - Molecular and Nutritional Epidemiology Unit
42 Clinical Genetics Service
43 Department of Pathology
44 University Medical Center [Utrecht]
45 MAP5 - UMR 8145 - Mathématiques Appliquées Paris 5
46 Department of Oncology
47 Department of Epidemiology and Biostatistics
48 Department of Visceral and Thoracic Surgery [Kiel, Germany]
49 Nutritional Epidemiology Unit
50 entre for Molecular, Environmental, Genetic and Analytic (MEGA) Epidemiology
51 FHCRC - Fred Hutchinson Cancer Research Center [Seattle]
52 Department of Laboratory Medicine and Department of Pathology
53 Department of Molecular Virology, Immunology and Medical Genetics [Colombus]
54 Department of Hygiene, Epidemiology and Medical Statistics
55 Department of Medical Biosciences and Pathology
56 Memorial Sloane Kettering Cancer Center [New York]
57 Institute of Experimental Medicine
58 Dundee Technopole
59 Karolinska Institutet [Stockholm]
60 CINTRA / SEEE Nanyang Technological University
61 CAS - Center for Astrophysical Sciences [Baltimore]
62 Computer Science and Artificial Intelligence Laboratory (CSAIL)
63 Department of Preventive Medicine
64 Biomedical Research Centre Network for Rare Diseases
65 Medstar Research Institute
66 GS - Department of Genome Sciences [Seattle]
67 Department of Internal Medicine, Epidemiology, Human Genetics
68 University of Oxford
Stephanie Bien
  • Function : Author
Tabitha Harrison
  • Function : Author
Hyun Min Kang
  • Function : Author
Sai Chen
  • Function : Author
Stephanie Schmit
  • Function : Author
David Conti
  • Function : Author
Conghui Qu
  • Function : Author
Jihyoun Jeon
  • Function : Author
Christopher Edlund
  • Function : Author
Peyton Greenside
  • Function : Author
Michael Wainberg
  • Function : Author
Joshua Smith
  • Function : Author
David Levine
  • Function : Author
Sarah Nelson
  • Function : Author
Nasa Sinnott-Armstrong
  • Function : Author
M. Henar Alonso
  • Function : Author
Kristin Anderson
  • Function : Author
Coral Arnau-Collell
  • Function : Author
Barbara Banbury
  • Function : Author
John Baron
  • Function : Author
Stéphane Bézieau
  • Function : Author
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D. Timothy Bishop
  • Function : Author
Juergen Boehm
  • Function : Author
Stefanie Brezina
  • Function : Author
Stephan Buch
  • Function : Author
Daniel Buch
  • Function : Author
Andrea Burnett-Hartman
  • Function : Author
Katja Butterbach
  • Function : Author
  • PersonId : 910629
Bette Caan
  • Function : Author
Christopher Carlson
  • Function : Author
Sergi Castellví-Bel
  • Function : Author
Andrew Chan
  • Function : Author
Stephen Chan
Sang Hee Cho
  • Function : Author
Charles Connolly
  • Function : Author
Amanda Cross
  • Function : Author
Katarina Cuk
  • Function : Author
Kimberly Doheny
  • Function : Author
David Duggan
  • Function : Author
Douglas Easton
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Sjoerd Elias
  • Function : Author
Faye Elliott
  • Function : Author
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Edith Feskens
Jane Figueiredo
  • Function : Author
Rocky Fischer
  • Function : Author
Manish Gala
  • Function : Author
W. James Gauderman
  • Function : Author
Elizabeth Gillanders
  • Function : Author
Jian Gong
Phyllis Goodman
  • Function : Author
William Grady
  • Function : Author
John Grove
  • Function : Author
Andrea Gsur
  • Function : Author
Robert Haile
  • Function : Author
Jochen Hampe
  • Function : Author
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Heather Hampe
  • Function : Author
Sophia Harlid
Philipp Hofer
  • Function : Author
Wan-Ling Hsu
  • Function : Author
Wen-Yi Huang
  • Function : Author
Gemma Ibañez-Sanz
  • Function : Author
Gregory Idos
  • Function : Author
Roxann Ingersoll
  • Function : Author
Rebecca Jackson
Eric Jacobs
  • Function : Author
Mark Jenkins
  • Function : Author
Corinne Joshu
  • Function : Author
Temitope Keku
  • Function : Author
Hyeong Rok Kim
  • Function : Author
Emiko Kobayashi
  • Function : Author
Laurence Kolonel
  • Function : Author
Charles Kooperberg
  • Function : Author
Sun-Seog Kweon
  • Function : Author
Susanna Larsson
  • Function : Author
Cecelia Laurie
  • Function : Author
Marc Le Marchand
  • Function : Author
Christopher Li
  • Function : Author
Li Li
Tin Louie
  • Function : Author
Mark Markowitz
  • Function : Author
Vicente Martín
Caroline Mcneil
  • Function : Author
Marilena Melas
  • Function : Author
Lorena Moreno
  • Function : Author
Neil Murphy
  • Function : Author
Robin Myte
  • Function : Author
Alessio Naccarati
Polly Newcomb
  • Function : Author
Kenneth Offit
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Shuji Ogino
  • Function : Author
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Barbara Pardini
  • Function : Author
Patrick Parfrey
  • Function : Author
Rachel Pearlman
  • Function : Author
Paul Pharoah
  • Function : Author
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Mila Pinchev
  • Function : Author
Elizabeth Platz
  • Function : Author
Ross Prentice
  • Function : Author
Elizabeth Pugh
  • Function : Author
Leon Raskin
  • Function : Author
Hedy Rennert
  • Function : Author
Elio Riboli
Miguel Rodríguez-Barranco
  • Function : Author
Jane Romm
  • Function : Author
Lori Sakoda
  • Function : Author
Robert Schoen
  • Function : Author
Daniel Seminara
  • Function : Author
Mitul Shah
  • Function : Author
Tameka Shelford
  • Function : Author
Min-Ho Shin
  • Function : Author
Katerina Shulman
  • Function : Author
Sabina Sieri
Martha Slattery
  • Function : Author
Zsofia Stadler
  • Function : Author
Christa Stegmaier
  • Function : Author
Yu-Ru Su
  • Function : Author
Thomas Thomas
  • Function : Author
Thomas Su
  • Function : Author
Cornelia Ulrich
  • Function : Author
David van den Berg
  • Function : Author
Franzel van Duijnhoven
  • Function : Author
Henk van Kranen
  • Function : Author
Kala Visvanathan
  • Function : Author
Ludmila Vodickova
  • Function : Author
Veronika Vymetalkova
  • Function : Author
Korbinian Weigl
  • Function : Author
Stephanie Weinstein
  • Function : Author
Emily White
  • Function : Author
Aung Ko Win
  • Function : Author
C. Roland Wolf
  • Function : Author
Alicja Wolk
Michael Woods
  • Function : Author
Anna Wu
  • Function : Author
Syed Zaidi
  • Function : Author
Brent Zanke
  • Function : Author
Peter Scacheri
  • Function : Author
John Potter
  • Function : Author
Michael Bassik
  • Function : Author
Goncalo Abecasis
  • Function : Author
  • PersonId : 948452
Li Hsu
  • Function : Author

Dates and versions

hal-02153497 , version 1 (12-06-2019)

Identifiers

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Jeroen Huyghe, Stephanie Bien, Tabitha Harrison, Hyun Min Kang, Sai Chen, et al.. Discovery of common and rare genetic risk variants for colorectal cancer. Nature Genetics, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩. ⟨hal-02153497⟩
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