Planar Chiral Phosphoramidites with a Paracyclophane Scaffold: Synthesis, Gold(I) Complexes, and Enantioselective Cycloisomerization of Dienynes - Archive ouverte HAL Access content directly
Journal Articles Chemistry - A European Journal Year : 2016

Planar Chiral Phosphoramidites with a Paracyclophane Scaffold: Synthesis, Gold(I) Complexes, and Enantioselective Cycloisomerization of Dienynes

Abstract

The key structuralf eature of the new phosphor-amidites is ap aracyclophane scaffoldi nw hich two aryl rings are tethered by both a1 ,8-biphenylene unit and aO ÀPÀOb ridge. Suitable aryl substituents generate planar chirality.T he corresponding gold(I) complexes promote the cycloisomerization of prochiral nitrogen-tethered dienynes. These reactions afford bicyclo[4.1.0]hep-tene derivatives displaying three contiguous stereogenic centers, with very high diastereoselectivity and up to 95 % ee.
Fichier principal
Vignette du fichier
CEJ BETZER - version HAL.pdf (734.67 Ko) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

hal-02152297 , version 1 (20-09-2019)

Identifiers

Cite

Zhiyong Wu, Kevin Isaac, Pascal ́ Retailleau, Jean-François Betzer, Arnaud Voituriez, et al.. Planar Chiral Phosphoramidites with a Paracyclophane Scaffold: Synthesis, Gold(I) Complexes, and Enantioselective Cycloisomerization of Dienynes. Chemistry - A European Journal, 2016, 22 (10), pp.3278-3281. ⟨10.1002/chem.201504658⟩. ⟨hal-02152297⟩
116 View
96 Download

Altmetric

Share

Gmail Facebook X LinkedIn More