Magnetic polymer 'nanopills'
Résumé
With specialist knowledge of polymer-based, self-assembled nanoparticles, the Laboratoire de Chimie des Polymères Organiques shares developments in polymer synthesis and polymer materials. We are a group of 5 tenured academic researchers and about 15 non-permanent researchers in the Laboratoire de Chimie des Polymères Organiques, a joint research unit of CNRS, University of Bordeaux, and Bordeaux National Polytechnic Institute, dedicated to polymer synthesis and polymer materials. More precisely, our group develops polymer-based self-assembled nanoparticles with high loading rates of active pharmaceutical ingredient (anticancer drugs, peptides, proteins...), multi-modal labelling (MRI, NIR...) and targeting (e.g. mAb). Our know-how includes the synthesis of biocompatible polymers such as polypeptides (by chemical synthesis or recombinant route), polysacharrides, and their combination as copolymers. We have a more than 1 decade experience in the design of multifunctional polymer vesicles called "polymersomes" loaded with drugs, iron oxide nanoparticles, grafted to antibodies, and several patents including one licensed to a pharmaceutical company located in Lyon (Adocia). We have some experience as participant in European projects, including a FP7 large NMP project (NANOTHER), which led to very promising results and productive interactions with biomedical companies, and we are now seeking to be active partners of a new H2020 project on nanomedicine.
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Magnetic Polymer Nanopills PAN_S&T12_200-201_2014.pdf (355.67 Ko)
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